Anti-FKBP10 Antibody Picoband®

Overview

Anti-FKBP10 Antibody Picoband® is an antibody for FKBP10 detection raised in Rabbit (Polyclonal, Rabbit IgG), with reported reactivity: Human. Commonly used in WB, IHC, IF, ICC, Flow Cytometry, ELISA workflows.

Key elements and design rationale

• Target: FKBP10 (histone deacetylase 10); UniProt: Q96AY3
• Antibody format: Rabbit, Polyclonal, Rabbit IgG
• Molecular weight: 72 kDa, calculated 39411 MW
• Applications: WB, IHC, IF, ICC, Flow Cytometry, ELISA

Vendor description (summary): Boster Bio Anti-FKBP10 Antibody Picoband® catalog # A05217-1.

Biological background

Biological context: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.

Expression and localization notes: cellular localization: Cytoplasm. Nucleus. Excluded from the nucleoli., tissue context: Ubiquitous. High expression in liver, spleen, pancreas and kidney..

Common research applications

• Western blotting (WB): Compare FKBP10 levels across samples and conditions using appropriate loading and biological controls.
• Immunohistochemistry (IHC): Evaluate spatial distribution of FKBP10 in tissue sections, considering fixation and antigen retrieval effects.
• Immunofluorescence / ICC: Assess subcellular localization patterns and co-localization with compartment markers in cultured cells.
• Flow cytometry: Quantify FKBP10-positive populations in single-cell suspensions with appropriate gating and controls.
• ELISA: Use antibody-based detection formats to assess antigen presence or binding in plate-based assays.

Notes for experimental interpretation

• Account for isoforms, post-translational modifications, and sample-specific processing that can shift apparent molecular weight or epitope accessibility.
• Use positive/negative biological controls where possible (e.g., known-expressing cells/tissues, knockdown/knockout models) and include appropriate secondary-only/isotype controls for imaging workflows.

Additional product notes (from provided fields)

• Background: FK506-binding protein 10 is a protein that in humans is encoded by the FKBP10 gene. The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. This protein localizes to the endoplasmic reticulum and acts as a molecular chaperone. Alternatively spliced variants encoding different isoforms have been reported, but their biological validity has not been determined.
• Cross reactivity: No cross-reactivity with other proteins.
• Cellular localization: Cytoplasm. Nucleus. Excluded from the nucleoli.
• Tissue details: Ubiquitous. High expression in liver, spleen, pancreas and kidney.
• Research category: Acetylation,Chromatin Modifying Enzymes,Class I,Epigenetics and Nuclear Signaling,Signaling Pathways,Stem Cells

Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.