| Field | Specification |
|---|---|
| Target | |
| Alternative names | Gamma-aminobutyric acid receptor subunit beta-1; GABA(A) receptor subunit beta-1; GABAAR subunit beta-1; GABRB1 |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human GABA A Receptor beta 1 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 18G39 is a rabbit monoclonal antibody that recognizes gamma-aminobutyric acid receptor subunit beta-1 (gene GABRB1) in human, mouse and rat samples and is validated for Western blot. The predicted molecular weight is 54.2 kDa, and the supplier reports an observed band at about 48 kDa.
GABRB1 encodes the β1 subunit of the GABA(A) receptor, a pentameric chloride channel opened by GABA. β subunits combine with α subunits to form the GABA binding sites, and the subunit mix defines receptor pharmacology. GABRB1 is studied in inhibitory neurotransmission, and variants have been reported in epileptic encephalopathy.
| Target | Gamma-aminobutyric acid receptor subunit beta-1 (gene GABRB1; UniProt P18505, human) |
|---|---|
| Clone | 18G39 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 54.2 kDa |
| Observed MW | 48 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|
Samples with a confirmed band (WB): human cerebellum.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of human GABA A Receptor beta 1.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places gamma-aminobutyric acid receptor subunit beta-1 in the postsynaptic cell membrane and cell membrane. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
