| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Glutamate--cysteine ligase catalytic subunit;6.3.2.2;GCS heavy chain;Gamma-ECS;Gamma-glutamylcysteine synthetase;GCLC;GLCL, GLCLC; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | A synthesized peptide derived from human GCLC |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Overview
Anti-GCLC Rabbit Monoclonal Antibody is an antibody targeting GCLC. Common applications include WB. Key specifications include host: Rabbit; clonality: Monoclonal; clone: Clone: ABBG-7; isotype: Rabbit IgG; reactivity: Human,Rat; observed MW: 68 kDa; calculated MW: 72766 MW.
Boster Bio Anti-GCLC Rabbit Monoclonal Antibody catalog # M01722. Tested in WB application. This antibody reacts with Human, Rat.
Key elements and design rationale
- Target: GCLC — Glutamate--cysteine ligase catalytic subunit
- Antibody format: Host: Rabbit; Clonality: Monoclonal; Clone: Clone: ABBG-7; Isotype: Rabbit IgG
- Species reactivity: Human,Rat
- Molecular weight guidance: Observed: 68 kDa; Calculated: 72766 MW
Biological background
Protein function (datasheet): Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Cellular localization (datasheet): Membrane; Multi-pass membrane protein.
Tissue details (datasheet): Expressed in numerous tissues with highest level in testis. .
Research relevance and current trends
- Commonly studied in contexts related to Cancer,Cell Biology,Metabolism,Mitochondrial,Mitochondrial Markers,Mitochondrial Metabolism,Oxidative Stress,Pathways and Processes,Redox Metabolism,Signal Transduction.
- Supports comparative expression analysis across conditions, genotypes, or treatments when paired with appropriate controls.
- Useful for confirming target presence and subcellular distribution using orthogonal readouts (e.g., microscopy vs. immunoblotting).
Common research applications
- Western blot (WB): Compare relative target abundance and apparent size/isoforms across samples; interpret bands in light of expected MW and potential PTMs.
Notes for experimental interpretation
- Consider isoforms, post-translational modifications, and processing that can shift apparent molecular weight or localization.
- Use appropriate positive and negative controls (e.g., KO/KD, blocking peptide, or isotype controls) to support specificity interpretation.
As a monoclonal antibody, this reagent is expected to recognize a defined epitope, which can support consistency across lots when epitope accessibility is preserved.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
