| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Homeobox protein Hox-A10;Homeobox protein Hox-1.8;Homeobox protein Hox-1H;PL;HOXA10;HOX1H; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | E.coli-derived human HOXA10 recombinant protein (Position: Y57-R340). Human HOXA10 shares 87% amino acid (aa) sequence identity with mouse HOXA10. |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Overview
This antibody is intended for detection of HOXA10 (Homeobox protein Hox-A10) in biological samples using common immunoassay formats. It is typically selected based on target identity, species reactivity, clonality/clone information, and detection modality.
Vendor notes: Boster Bio Anti-HOXA10 Antibody Picoband® catalog # PB9217. Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key elements and design rationale
- Antibody format: Rabbit Polyclonal Rabbit IgG
- Immunogen / epitope context: E.coli-derived human HOXA10 recombinant protein (Position: Y57-R340). Human HOXA10 shares 87% amino acid (aa) sequence identity with mouse HOXA10. (reported region: Y57-R340).
- Molecular weight context: reported MW: 41 kDa; calculated MW: 42414 MW
- Reactivity: Human,Rat
- Applications: WB
As a polyclonal antibody, the reagent recognizes multiple epitopes on the target, which can improve detection robustness but may increase sensitivity to sample-dependent epitope changes.
Biological background
Homeobox protein Hox-A10; Homeobox protein Hox-A10. Homeobox protein Hox-A10 is a protein that in humans is encoded by the HOXA10 gene. HOXA10 is expressed in the adult human endometrium, and the expression of HOXA10 dramatically increased during the midsecretory phase of the menstrual cycle, corresponding to the time of implantation and increase in circulating progesterone. HOXA10 may have an important function in regulating endometrial development during the menstrual cycle and in establishing conditions necessary for implantation in the human. HOXA10 is also a master regulator of postnatal hematopoietic development whose tight regulation is required for normal development of erythroid and megakaryocytic lineages. Functional note: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to the DNA sequence 5'-AA[AT]TTTTATTAC-3'. Reported localization: Nucleus.
Research relevance and current trends
- Developmental Families: Researchers commonly examine how HOXA10 (Homeobox protein Hox-A10) relates to this theme using model systems and orthogonal readouts.
- Domain Families: Researchers commonly examine how HOXA10 (Homeobox protein Hox-A10) relates to this theme using model systems and orthogonal readouts.
- Epigenetics and Nuclear Signaling: Researchers commonly examine how HOXA10 (Homeobox protein Hox-A10) relates to this theme using model systems and orthogonal readouts.
Common research applications
- Western blotting: compare relative HOXA10 (Homeobox protein Hox-A10) levels across conditions; band patterns may reflect isoforms and processing.
Notes for experimental interpretation
- Specificity notes: No cross reactivity with other proteins.
- Cross-reactivity: No cross-reactivity with other proteins
- Family / similarity context: Belongs to the Abd-B homeobox family.
- Isoforms and PTMs: Apparent size and signal patterns can differ across splice isoforms, proteolytic processing, and post-translational modifications.
- Controls: Include an isotype control (as relevant), no-primary control for imaging, and orthogonal validation such as KD/KO samples when available.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
