| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | ANX005, ANX005, ANX-005 |
| Clonality | |
| Expression System | |
| Form | Liquid |
| Host | |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage | |
| Target | |
| UniProt # |
Product Overview
Anti-Human C1q Antibody (ANX005) (HY334016) is a research-grade recombinant antibody targeting C1QA. Produced in mammalian cells with native-like glycosylation. Highlights- ●Research Grade — For PK/PD studies, assay development, and ADA research.
- ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Specifications
| Host Species | Human |
|---|---|
| Species Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | IgG |
| Clone | ANX005 |
| Target | C1QA, Complement C1q subcomponent subunit A |
| Purification | Protein A/G purified from cell culture supernatant. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Form | Liquid |
| Storage Buffer | 0.01M PBS, pH 7.4. |
| Expression System | Mammalian Cells |
| UniProt | P02745 |
Validated Applications
| Application |
|---|
| ELISA |
| Flow Cytometry |
| Functional Assay |
| In Vivo Studies |
Scientific Background
Complement C1q subcomponent subunit A (C1QA) is a ~26 kDa protein. Core component of the complement C1 complex, which initiates the classical pathway of the complement system, a cascade leading to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system.
Reactivity
This antibody shows reactivity with Human.
Safety & Handling
Customization & Add-ons: Can't find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
1. Kishore, U. et al. (2003) Journal of immunology 171, 812-20. PMID: 12847249
2. Gadjeva, MG. et al. (2008) Biochemistry 47, 13093-102. PMID: 19006321
3. Diebolder, CA. et al. (2014) Science 343, 1260-3. PMID: 24626930
4. Ugurlar, D. et al. (2018) Science 359, 794-797. PMID: 29449492
5. Duncan, AR. et al. (1988) Nature 332, 738-40. PMID: 3258649
6. Zwarthoff, SA. et al. (2021) PNAS 118. PMID: 34155115
7. Lin, TY. et al. (1980) J Biol Chem 255, 7756-62. PMID: 6249812
8. Burton, DR. et al. (1980) Nature 288, 338-44. PMID: 6776418
