| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Low affinity neurotrophin receptor p75NTR, TNFRSF16, CD271, Gp80-LNGFR, p75 ICD, Low-affinity nerve growth factor receptor, NGFR, NGF receptor, Tumor necrosis factor receptor superfamily member 16 |
| Clonality | |
| Concentration | |
| Conjugate | |
| Form | Liquid |
| Host | |
| Isotype | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Overview
Anti-Human CD271/NGFR Antibody (T-2), APC targets CD271 (Tumor necrosis factor receptor superfamily member 16). Frequently used across ELISA, FCM workflows, depending on experimental design and sample type. This antibody is suited for workflows commonly used in Neuroscience research.
Also known as: Tumor necrosis factor receptor superfamily member 16, Low-affinity nerve growth factor receptor, Low affinity neurotrophin receptor p75NTR, NGF receptor, p75 ICD, Gp80-LNGFR, TNFRSF16, NGFR.
Target biology
CD271 (Tumor necrosis factor receptor superfamily member 16) encodes a receptor or receptor subunit involved in sensing extracellular or cell-surface cues and relaying signals to intracellular pathways. Receptor availability at the cell surface and activation state can vary with differentiation and stimulation conditions. Common alternative names and symbols used in the literature include: Low-affinity nerve growth factor receptor, Low affinity neurotrophin receptor p75NTR, NGF receptor, p75 ICD, Gp80-LNGFR, TNFRSF16, NGFR. Based on the annotated name/class, the target is most often associated with secreted / extracellular localization, though this can vary by model system.
How this antibody helps
As a monoclonal reagent, this antibody is designed for clone-to-clone consistency and epitope-focused recognition. For best performance, interpret signal in the context of appropriate biological controls and orthogonal readouts when available.
Recommended experimental notes
- Titrate the antibody to optimize signal-to-noise for your specific sample type and detection system.
- Use appropriate positive and negative controls (e.g., target-high vs target-low samples, KO/KD where available).
- For ELISA, optimize capture/detection pairing and run a standard curve in matrix-matched diluent when possible.
For research use only. Not for diagnostic procedures.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
