| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | ZM008 |
| Clonality | |
| Expression System | |
| Form | Liquid |
| Host | |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage | |
| Target | |
| UniProt # |
Product Overview
Anti-Human CLEC2D/OCIL/LLT1 (ZM008) (HP960016) is a research-grade recombinant antibody targeting CLAX. Produced in mammalian cells with native-like glycosylation.HIGHLIGHTS
●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.
Specifications
| Host Species | Human |
|---|---|
| Species Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | IgG |
| Clone | ZM008 |
| Target | CLAX, C-type lectin domain family 2 member D, Osteoclast inhibitory lectin, CLEC2D, Lectin-like transcript 1, Lectin-like NK cell receptor, OCIL, LLT-1, LLT1 |
| Purification | Protein A/G purified from cell culture supernatant. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Form | Liquid |
| Storage Buffer | 0.01M PBS, pH 7.4. |
| Expression System | Mammalian Cells |
| UniProt | Q9UHP7 |
Validated Applications
| Application |
|---|
| ELISA |
| Flow Cytometry |
| Functional Assay |
| In Vivo Studies |
Scientific Background
C-type lectin domain family 2 member D (CLEC2D/OCIL) is a ~21 kDa protein. Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon-gamma. Binds high molecular weight sulfated glycosaminoglycans.
Reactivity
This antibody shows reactivity with Human.
Safety & Handling
Customization & Add-ons: Can't find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
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3. Hu, YS. et al. (2004) Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 19, 89-99. PMID: 14753741
4. Gange, CT. et al. (2004) The Journal of biological chemistry 279, 29043-9. PMID: 15123656
5. Mathew, PA. et al. (2004) Molecular immunology 40, 1157-63. PMID: 15104121
