Anti-Human IL-4 Reference Antibody (Pascolizumab)

SKU:BHA21415935
Research Validated
Suppliers
Overview
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Anti-Human IL-4 Reference Antibody (Pascolizumab) is a research-grade recombinant reference antibody (Humanized, Monoclonal, IgG1, kappa) targeting Binetrakin. Validated for ELISA, Flow Cytometry, Functional Assay.
Clonality Monoclonal
Host Species Humanized
Reactivity Human
Isotype IgG1, kappa
Applications ELISA, Flow Cytometry, Functional Assay, In Vivo Studies
Options selector
Catalog no. Size
HY457016-1MG 1 mg
HY457016-5MG 5 mg
HY457016-10MG 10 mg
HY457016-25MG 25 mg
HY457016-50MG 50 mg
HY457016-100MG 100 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 1 mg / 5 mg / 10 mg / 25 mg / 50 mg / 100 mg
  • Lead time: options listed in "Availability Content"; other statuses may take longer.
  • Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
  • Shipping: cold-chain shipment (typically with ice packs).
  • Upon receipt: store at recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No HY457016
Alternative Names SB-240683
Cas No. 331243-22-2
Clonality
  • Monoclonal
Expression System
  • Mammalian Cells
Form Liquid
Host Humanized
Isotype
  • IgG1
  • kappa
Product Type
  • Biosimilars
Purity >95% (SDS-PAGE)
Reactivity
  • Human
Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Target Binetrakin
UniProt # P05112
Reference Antibody

Product Overview

Research Grade Pascolizumab (HY457016) is a humanized monoclonal antibody detecting Binetrakin in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human. Highlights
  • Multi-Application — Validated across multiple applications.

Specifications

Host Species Humanized
Species Reactivity Human
Clonality Monoclonal
Isotype IgG1, kappa
Target Binetrakin, B-cell stimulatory factor 1, Pitrakinra, Lymphocyte stimulatory factor 1, IL-4, BSF-1, IL4, Interleukin-4
Purification Protein A/G purified from cell culture supernatant.
Purity >95% purity as determined by SDS-PAGE.
Form Liquid
Storage Buffer 0.01M PBS, pH 7.4.
Expression System Mammalian Cells
UniProt P05112

Validated Applications

Application
ELISA
Flow Cytometry
Functional Assay
In Vivo Studies

Scientific Background

Interleukin-4 (Binetrakin, B-cell stimulatory factor 1, Pitrakinra, IL-4, BSF-1, IL4) is a ~17 kDa protein. Cytokine secreted primarily by mast cells, T-cells, eosinophils, and basophils that plays a role in regulating antibody production, hematopoiesis and inflammation, and the development of effector T-cell responses.

Reactivity

This antibody shows reactivity with Human.

Safety & Handling

For Research Use Only (RUO). Not for use in diagnostic or therapeutic procedures.
Q.What applications is this antibody validated for?
A.This reference antibody is validated for ELISA, Flow Cytometry, Functional Assay, In Vivo Studies. Optimize dilutions in your own experimental system.
Q.What species or target does it react with?
A.It shows reactivity with Human.
Q.What are the clonality and isotype?
A.It is Monoclonal, isotype IgG1, kappa.
Q.Is this product research-grade?
A.Yes. All products are For Research Use Only (RUO) and are not intended for diagnostic or therapeutic use.
Q.Can I request bulk quantities or custom formats?
A.Yes. Contact us for bulk orders, custom conjugation, or special formulations.

Customization & Add-ons: Can't find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.

1. Carr, C. et al. (1991) Biochemistry 30, 1515-23. PMID: 1993171

2. Yokota, T. et al. (1986) Proceedings of the National Academy of Sciences of the United States of America 83, 5894-8. PMID: 3016727

3. Delespesse, G. et al. (1989) Journal of immunology (Baltimore, Md. : 1950) 142, 134-8. PMID: 2521231

4. Hage, T. et al. (1999) Cell 97, 271-81. PMID: 10219247

5. Hülsmeyer, M. et al. (2001) Acta crystallographica. Section D, Biological crystallography 57, 1334-6. PMID: 11526337

6. LaPorte, SL. et al. (2008) Cell 132, 259-72. PMID: 18243101

7. Malabarba, MG. et al. (1995) The Journal of biological chemistry 270, 9630-7. PMID: 7721895

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Please use this form for bulk quantity requests or customized products.

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Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

Try Celltrypse Free – Request Your Sample Today