| Field | Specification |
|---|---|
| Target | |
| Alternative names | Importin subunit alpha-1;Karyopherin subunit alpha-2;RAG cohort protein 1;SRP1-alpha;KPNA2;RCH1, SRP1; |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human KPNA2, different from the related mouse sequence by three amino acids. |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody targets importin subunit alpha-1 (gene KPNA2) in human samples and is validated for Western blot.
Importin α1 (KPNA2) is an adapter that binds classical nuclear localization signals on cargo proteins and links them to importin β1 for transport through the nuclear pore, with RanGTP triggering release inside the nucleus. KPNA2 is highly expressed in proliferating cells and is often elevated in tumors, making it a subject of cancer research.
| Target | Importin subunit alpha-1 (gene KPNA2; UniProt P52292, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / Rabbit IgG |
| Reactivity | Human |
| Purification | Immunogen affinity purified |
| Form | Lyophilized |
| Formulation | Per vial: 0.9 mg NaCl; 0.2 mg Na2HPO4; 0.05 mg NaN3; plus stabilizers |
| Reconstitution | 500 µg/mL after adding 0.2 mL distilled water |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 0.1–0.5 µg/mL (Human) |
|---|
Immunogen
Synthetic peptide from the N-terminal region of human KPNA2. It differs from the mouse sequence at three residues.
Reactivity Notes
The supplier lists reactivity with human. UniProt places importin subunit alpha-1 in the cytoplasm, nucleus and Golgi apparatus membrane. Tissue expression noted by UniProt (human): Expressed ubiquitously.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
