| Field | Specification |
|---|---|
| Target | |
| Alternative names | Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2; Leucine-rich repeat neuronal protein 3; Leucine-rich repeat neuronal protein 6C; LINGO2; LERN3; LRRN6C |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | E.coli-derived human LINGO2 recombinant protein (Position: C28-R513). Human LINGO2 shares 97.9% amino acid (aa) sequence identity with mouse LINGO2. |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody detects leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 (gene LINGO2) in human, mouse and rat samples and is validated for Western blot and ELISA.
LINGO2 is a transmembrane protein with leucine-rich repeats and an immunoglobulin-like domain, expressed mainly in the brain. It is related to LINGO1, a component of the Nogo receptor complex, but its own function is not fully characterized. LINGO2 is studied mainly in neuroscience.
| Target | Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 (gene LINGO2; UniProt Q7L985, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / IgG |
| Reactivity | Human, Mouse, Rat |
| Purification | Immunogen affinity purified |
| Form | Lyophilized |
| Formulation | Per vial: 4 mg trehalose; 0.9 mg NaCl; 0.2 mg Na2HPO4 |
| Reconstitution | 500 µg/mL after adding 0.2 mL distilled water |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 0.25–0.5 µg/mL (Human, Mouse, Rat) |
|---|---|
| ELISA | 0.1–0.5 µg/mL |
Immunogen
Recombinant human LINGO2 fragment (Cys28–Arg513), expressed in E. coli. Sequence identity with the mouse ortholog: 97.9%.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 in the membrane.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
