| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Microtubule-associated protein 1A;MAP-1A;MAP1A heavy chain;MAP1 light chain LC2;Map1a;Mtap1a; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Gene ID | |
| Host | |
| Immunogen | Rat brain microtubule-associated proteins (MAPs). |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Overview
Anti-MAP1 Antibody (Monoclonal, HM-1) is an antibody targeting MAP1A. Common applications include WB, IHC. Key specifications include host: Mouse; clonality: Monoclonal; clone: Clone: HM-1; isotype: Mouse IgG1; reactivity: Mouse,Rat; observed MW: 42 kDa; calculated MW: 299531 MW.
Boster Bio Anti-MAP1 Antibody (Monoclonal, HM-1) catalog # MA1056. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat.
Key elements and design rationale
- Target: MAP1A — Microtubule-associated protein 1A
- Antibody format: Host: Mouse; Clonality: Monoclonal; Clone: Clone: HM-1; Isotype: Mouse IgG1
- Species reactivity: Mouse,Rat
- Molecular weight guidance: Observed: 42 kDa; Calculated: 299531 MW
Specificity note: No cross reactivity with other proteins.
Biological background
Protein function (datasheet): Structural protein involved in the filamentous cross- bridging between microtubules and other skeletal elements.
Scientific background (datasheet): Microtubules are the ubiquitous cytoskeletal structural components that are involved in intracellular transport. They are composed of tubulin and microtubule-associated proteins (MAPs). MAP1 is one of the major neuronal MAPs as well as being the largest (350KD). MAPs include MAP1A, MAP1B, and MAP2. MAP1a is a single-copy gene spanning 10.5 kb. MAP1a coding sequence is contained in five exons. MAP1B is encoded as a polyprotein that is processed to form a complex N-terminal microtubule-binding domain.
Cellular localization (datasheet): Cytoplasm, cytoskeleton .
Tissue details (datasheet): Brain, heart and muscle.
Sequence similarities (datasheet): Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Research relevance and current trends
- Commonly studied in contexts related to Cytoskeleton,Cytoskeleton/ECM,Microtubules,Neurogenesis,Neurology Process,Neuroscience,Signal Transduction.
- Supports comparative expression analysis across conditions, genotypes, or treatments when paired with appropriate controls.
- Useful for confirming target presence and subcellular distribution using orthogonal readouts (e.g., microscopy vs. immunoblotting).
Common research applications
- Western blot (WB): Compare relative target abundance and apparent size/isoforms across samples; interpret bands in light of expected MW and potential PTMs.
- Immunohistochemistry (IHC): Assess tissue distribution and cell-type patterns; interpret staining with appropriate negative controls and antigen context.
Notes for experimental interpretation
- Consider isoforms, post-translational modifications, and processing that can shift apparent molecular weight or localization.
- Cross-reactivity (datasheet): No cross-reactivity with other proteins
- Use appropriate positive and negative controls (e.g., KO/KD, blocking peptide, or isotype controls) to support specificity interpretation.
As a monoclonal antibody, this reagent is expected to recognize a defined epitope, which can support consistency across lots when epitope accessibility is preserved.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
