| Field | Specification |
|---|---|
| Target | |
| Alternative names | Microtubule-associated protein 2;MAP-2;Map2;Mtap2; |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Rat brain microtubule-associated proteins (MAPs). |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone HM-2 is a mouse monoclonal antibody that recognizes microtubule-associated protein 2 (gene Map2) in human, mouse and rat samples and is validated for Western blot and IHC.
Microtubule-associated protein 2 (MAP2) is a neuron-specific protein concentrated in dendrites and cell bodies. It binds and stabilizes microtubules and helps shape dendrites, and MAP2 immunostaining is one of the most widely used methods to identify neurons and visualize dendritic arbors.
| Target | Microtubule-associated protein 2 (gene Map2; UniProt P15146, rat) |
|---|---|
| Clone | HM-2 |
| Host / Clonality / Isotype | Mouse / Monoclonal / Mouse IgG1 |
| Reactivity | Human, Mouse, Rat |
| Purification | Ascites |
| Form | Lyophilized |
| Formulation | 1.2% sodium acetate; 0.01 mg NaN3; plus stabilizers |
| Reconstitution | 100 µg/mL after adding 1 mL PBS |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| IHC (paraffin sections) | 1–2 µg/mL (Human, Mouse, Rat) |
|---|---|
| Western blot | 0.5–2 µg/mL (Mouse, Rat) |
Immunogen
Rat brain microtubule-associated proteins (MAPs).
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places microtubule-associated protein 2 in the cytoplasm and cell projection. Tissue expression noted by UniProt (rat): Expressed in the liver...
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
Xiao Dongchang et al. (2018) Direct reprogramming of fibroblasts into neural stem cells by single non-neural progenitor transcription factor Ptf1a. Nature Communications. 10.1038/s41467-018-05209-1
Qin Tu et al. (2011) The effect of acetylcholine-like biomimetic polymers on neuronal growth. Biomaterials. 10.1016/j.biomaterials.2011.01.044
Yin Xu et al. (2012) Activation of the macroautophagic system in scrapie-infected experimental animals and human genetic prion diseases. Autophagy. 10.4161/auto.21482
Jiejie Zhuang et al. (2022) Brca1 Is Regulated by the Transcription Factor Gata3, and Its Silencing Promotes Neural Differentiation in Retinal Neurons. International Journal of Molecular Sciences. 10.3390/ijms232213860
Pei Chen et al. (2022) Gata3 Silencing Is Involved in Neuronal Differentiation and Its Abnormal Expression Impedes Neural Activity in Adult Retinal Neurocytes. International Journal of Molecular Sciences. 10.3390/ijms23052495
Kai You et al. (2018) MicroRNA-125b Promotes Hepatic Stellate Cell Activation and Liver Fibrosis by Activating RhoA Signaling. Molecular Therapy-Nucleic Acids. 10.1016/j.omtn.2018.04.016
Li Haoyuan et al. (2019) Melatonin Enhances Proliferation and Modulates Differentiation of Neural Stem Cells Via Autophagy in Hyperglycemia. Stem Cells. 10.1002/stem.2968
Li-Min Zhang et al. (2022) STING mediates neuroinflammatory response by activating NLRP3-related pyroptosis in severe traumatic brain injury. Journal of Neurochemistry. 10.1111/jnc.15678
Hao Huang et al. (2017) Nitrobenzylthioinosine mimics adenosine to attenuate the epileptiform discharge of hippocampal neurons from epileptic rats. Oncotarget. 10.18632/oncotarget.16012
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