| Field | Specification |
|---|---|
| Target | |
| Alternative names | Meteorin-like protein; Subfatin; METRNL |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | E.coli-derived human METRNL recombinant protein (Position: K66-D311). Human METRNL shares 78.5% and 79.3% amino acid (aa) sequence identity with mouse and rat METRNL, respectively. |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody targets meteorin-like protein (gene METRNL) in human samples and is validated for Western blot and ELISA.
Meteorin-like (METRNL) is a secreted protein, related to meteorin, that is induced in skeletal muscle by exercise and in adipose tissue by cold. It recruits and activates immune cells, including eosinophils and alternatively activated macrophages, which promote browning of white fat and energy expenditure. METRNL is studied in metabolism, inflammation and muscle repair.
| Target | Meteorin-like protein (gene METRNL; UniProt Q641Q3, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / IgG |
| Reactivity | Human |
| Purification | Immunogen affinity purified |
| Form | Lyophilized |
| Formulation | Per vial: 4 mg trehalose; 0.9 mg NaCl; 0.2 mg Na2HPO4 |
| Reconstitution | 500 µg/mL after adding 0.2 mL distilled water |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 0.25–0.5 µg/mL (Human) |
|---|---|
| ELISA | 0.1–0.5 µg/mL |
Immunogen
Recombinant human METRNL fragment (Lys66–Asp311), expressed in E. coli. Sequence identity with the mouse and rat orthologs: 78.5% and 79.3%, respectively.
Reactivity Notes
The supplier lists reactivity with human. UniProt describes meteorin-like protein as a secreted protein. Tissue expression noted by UniProt (human): Highly expressed in the skeletal muscle, in subcutaneous adipose tissue, epididymal white adipose tissue depots and heart.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
