| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | IGF2R, M6P/IGF2 receptor, 300 kDa mannose 6-phosphate receptor, IGF-II receptor, M6PR, CI-MPR, CD222, Insulin-like growth factor 2 receptor, MPR 300, M6P/IGF2R, MPRI, CI Man-6-P receptor, Insulin-like growth factor II receptor, Cation-independent mannose-6-phosphate receptor |
| Clonality | |
| Concentration | |
| Conjugate | |
| Form | Liquid |
| Host | |
| Isotype | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Overview
Anti-Mouse CD20/MS4A1 Antibody (18B12), PerCP targets CD20 (Insulin-like growth factor II receptor). Frequently used across FCM, IF, WB workflows, depending on experimental design and sample type. This antibody is suited for workflows commonly used in Metabolism & Diabetes research.
Also known as: Insulin-like growth factor II receptor, Insulin-like growth factor 2 receptor, 300 kDa mannose 6-phosphate receptor, Cation-independent mannose-6-phosphate receptor, CI Man-6-P receptor, M6P/IGF2 receptor, IGF-II receptor, MPR 300, CI-MPR, M6P/IGF2R.
Target biology
CD20 (Insulin-like growth factor II receptor) encodes a receptor or receptor subunit involved in sensing extracellular or cell-surface cues and relaying signals to intracellular pathways. Receptor availability at the cell surface and activation state can vary with differentiation and stimulation conditions. Common alternative names and symbols used in the literature include: Insulin-like growth factor 2 receptor, 300 kDa mannose 6-phosphate receptor, Cation-independent mannose-6-phosphate receptor, CI Man-6-P receptor, M6P/IGF2 receptor, IGF-II receptor, MPR 300, CI-MPR, M6P/IGF2R, IGF2R. Based on the annotated name/class, the target is most often associated with secreted / extracellular localization, though this can vary by model system.
How this antibody helps
As a monoclonal reagent, this antibody is designed for clone-to-clone consistency and epitope-focused recognition. For best performance, interpret signal in the context of appropriate biological controls and orthogonal readouts when available.
Recommended experimental notes
- Titrate the antibody to optimize signal-to-noise for your specific sample type and detection system.
- Use appropriate positive and negative controls (e.g., target-high vs target-low samples, KO/KD where available).
- For Western blotting, use fresh protease (and phosphatase, if relevant) inhibitors and confirm the primary band at the expected molecular weight; additional bands may reflect isoforms or processing.
- For IF/ICC, test fixation (PFA vs methanol) and permeabilization conditions to preserve epitope accessibility while minimizing background.
For research use only. Not for diagnostic procedures.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
