| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Macrophage mannose receptor 1;MMR;C-type lectin domain family 13 member D;C-type lectin domain family 13 member D-like;Human mannose receptor;hMR;Macrophage mannose receptor 1-like protein 1;CD206;MRC1;CLEC13D, CLEC13DL, MRC1L1; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Gene ID | |
| Host | |
| Immunogen | A synthesized peptide derived from human MRC1 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Overview
Anti-MRC1/Cd206 Rabbit Monoclonal Antibody is an antibody targeting MRC1. Common applications include WB, ICC, IF. Key specifications include host: Rabbit; clonality: Monoclonal; clone: Clone: AOOF-13; isotype: Rabbit IgG; reactivity: Human; observed MW: 112 kDa; calculated MW: 166012 MW.
Boster Bio Anti-MRC1/Cd206 Rabbit Monoclonal Antibody catalog # M02285. Tested in WB, ICC/IF applications. This antibody reacts with Human.
Key elements and design rationale
- Target: MRC1 — Macrophage mannose receptor 1
- Antibody format: Host: Rabbit; Clonality: Monoclonal; Clone: Clone: AOOF-13; Isotype: Rabbit IgG
- Species reactivity: Human
- Molecular weight guidance: Observed: 112 kDa; Calculated: 166012 MW
Biological background
Protein function (datasheet): Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains.
Cellular localization (datasheet): Endosome membrane ; Single-pass type I membrane protein . Cell membrane ; Single-pass type I membrane protein .
Tissue details (datasheet): Expressed at high levels in the lung, liver placenta and pancreas. Moderate levels seen in the heart and skeletal muscle. Lower levels found in the brain and kidney. .
Research relevance and current trends
- Commonly studied in contexts related to Angiogenesis,Cancer,Cytokines,Immunology,Innate Immunity,Invasion/Microenvironment.
- Supports comparative expression analysis across conditions, genotypes, or treatments when paired with appropriate controls.
- Useful for confirming target presence and subcellular distribution using orthogonal readouts (e.g., microscopy vs. immunoblotting).
Common research applications
- Western blot (WB): Compare relative target abundance and apparent size/isoforms across samples; interpret bands in light of expected MW and potential PTMs.
- Immunofluorescence / ICC: Visualize subcellular localization and co-localization patterns; consider fixation/permeabilization compatibility and controls.
Notes for experimental interpretation
- Consider isoforms, post-translational modifications, and processing that can shift apparent molecular weight or localization.
- Use appropriate positive and negative controls (e.g., KO/KD, blocking peptide, or isotype controls) to support specificity interpretation.
As a monoclonal antibody, this reagent is expected to recognize a defined epitope, which can support consistency across lots when epitope accessibility is preserved.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
