| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Canalicular multispecific organic anion transporter 1;ATP-binding cassette sub-family C member 2;Canalicular multidrug resistance protein;Multidrug resistance-associated protein 2;ABCC2;CMOAT, CMOAT1, CMRP, MRP2; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | A synthesized peptide derived from human MRP2 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Overview
Anti-MRP2 ABCC2 Rabbit Monoclonal Antibody is an antibody targeting ABCC2. Common applications include WB, ICC, IF, Flow Cytometry. Key specifications include host: Rabbit; clonality: Monoclonal; clone: Clone: ABDD-1; isotype: Rabbit IgG; reactivity: Human; observed MW: 250 kDa; calculated MW: 174207 MW.
Boster Bio Anti-MRP2 ABCC2 Rabbit Monoclonal Antibody catalog # M00974. Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.
Key elements and design rationale
- Target: ABCC2 — Canalicular multispecific organic anion transporter 1
- Antibody format: Host: Rabbit; Clonality: Monoclonal; Clone: Clone: ABDD-1; Isotype: Rabbit IgG
- Species reactivity: Human
- Molecular weight guidance: Observed: 250 kDa; Calculated: 174207 MW
Biological background
Protein function (datasheet): Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter.
Cellular localization (datasheet): Apical cell membrane ; Multi-pass membrane protein .
Tissue details (datasheet): Expressed by polarized cells in liver, kidney and intestine. The highest expression is found in liver.
Research relevance and current trends
- Commonly studied in contexts related to Cancer,Channels,Metabolism,Plasma Membrane,Signal Transduction.
- Supports comparative expression analysis across conditions, genotypes, or treatments when paired with appropriate controls.
- Useful for confirming target presence and subcellular distribution using orthogonal readouts (e.g., microscopy vs. immunoblotting).
Common research applications
- Western blot (WB): Compare relative target abundance and apparent size/isoforms across samples; interpret bands in light of expected MW and potential PTMs.
- Immunofluorescence / ICC: Visualize subcellular localization and co-localization patterns; consider fixation/permeabilization compatibility and controls.
- Flow cytometry: Quantify target-positive populations in single-cell suspensions; pair with viability and isotype/FMO controls conceptually.
Notes for experimental interpretation
- Consider isoforms, post-translational modifications, and processing that can shift apparent molecular weight or localization.
- Use appropriate positive and negative controls (e.g., KO/KD, blocking peptide, or isotype controls) to support specificity interpretation.
As a monoclonal antibody, this reagent is expected to recognize a defined epitope, which can support consistency across lots when epitope accessibility is preserved.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
