| Field | Specification |
|---|---|
| Target | |
| Alternative names | N-glycosylase/DNA lyase; OGG1; MMH; MUTM; OGH1 |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human OGG1 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 17O52 is a rabbit monoclonal antibody that recognizes N-glycosylase/DNA lyase (gene OGG1) in human samples and is validated for Western blot. The predicted molecular weight is 38.8 kDa, and the supplier reports an observed band at about 39 kDa.
OGG1 (8-oxoguanine DNA glycosylase) is the main enzyme that removes 8-oxoguanine, a common oxidative lesion, from DNA. It excises the damaged base and nicks the DNA strand to begin base excision repair, so it is widely studied in oxidative stress, mutagenesis, aging and inflammation.
| Target | N-glycosylase/DNA lyase (gene OGG1; UniProt O15527, human) |
|---|---|
| Clone | 17O52 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 38.8 kDa |
| Observed MW | 39 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|
Immunogen
Synthetic peptide based on the sequence of human OGG1.
Reactivity Notes
The supplier lists reactivity with human. UniProt places N-glycosylase/DNA lyase in the nucleus, nucleus speckle and nucleus matrix. Tissue expression noted by UniProt (human): Ubiquitous.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
