| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Cyclin-dependent kinase 16 (EC:2.7.11.22); Cell division protein kinase 16; PCTAIRE-motif protein kinase 1; Serine/threonine-protein kinase PCTAIRE-1; CDK16; PCTAIRE1; PCTK1 |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | E.coli-derived human Olig1 recombinant protein (Position: M1-K271). |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Overview
Anti-Olig1 Antibody Picoband® is an antibody for OLIG1 detection raised in Rabbit (Polyclonal, Rabbit IgG), with reported reactivity: Human,Mouse,Rat. Commonly used in WB, IHC, Flow Cytometry, ELISA workflows.
Key elements and design rationale
- Target: OLIG1 (cyclin dependent kinase 16); UniProt: Q8TAK6
- Antibody format: Rabbit, Polyclonal, Rabbit IgG
- Molecular weight: 28 kDa, calculated 17828 MW
- Applications: WB, IHC, Flow Cytometry, ELISA
Vendor description (summary): Boster Bio Anti-Olig1 Antibody Picoband® catalog # A06108-3.
Biological background
Biological context: Protein kinase that plays a role in vesicle-mediated transport processes and exocytosis. Regulates GH1 release by brain neurons. Phosphorylates NSF, and thereby regulates NSF oligomerization. Required for normal spermatogenesis. Regulates neuron differentiation and dendrite development (By similarity). Plays a role in the regulation of insulin secretion in response to changes in blood glucose levels. Can phosphorylate CCNY at 'Ser-336' (in vitro).
Expression and localization notes: cellular localization: Cell membrane. Peripheral membrane protein. Cytoplasmic side. Cytoplasm. Secretory vesicle. Synaptosome., tissue context: Detected in pancreas islets (at protein level). Detected in brain and pancreas..
Common research applications
- Western blotting (WB): Compare OLIG1 levels across samples and conditions using appropriate loading and biological controls.
- Immunohistochemistry (IHC): Evaluate spatial distribution of OLIG1 in tissue sections, considering fixation and antigen retrieval effects.
- Flow cytometry: Quantify OLIG1-positive populations in single-cell suspensions with appropriate gating and controls.
- ELISA: Use antibody-based detection formats to assess antigen presence or binding in plate-based assays.
Notes for experimental interpretation
- Account for isoforms, post-translational modifications, and sample-specific processing that can shift apparent molecular weight or epitope accessibility.
- Use positive/negative biological controls where possible (e.g., known-expressing cells/tissues, knockdown/knockout models) and include appropriate secondary-only/isotype controls for imaging workflows.
Additional product notes (from provided fields)
- Background: Oligodendrocyte transcription factor 1 (OLIG1), also known as class B basic helix-loop-helix protein 6 (BHLHB6) is a protein that in humans is encoded by the OLIG1 gene. This gene is mapped to 21q22.11. This gene is a member of the oligodendrocyte lineage gene family which encodes basic helix-loop-helix transcription factors. Studies in mice show that it is coexpressed with Olig2 in neural progenitors, and has a role in the development and maturation of oligodendrocytes. OLIG1 gene promotes formation and maturation of oligodendrocytes, especially within the brain. It cooperates with OLIG2 to establish the pMN domain of the embryonic neural tube.
- Cross reactivity: No cross-reactivity with other proteins.
- Cellular localization: Cell membrane. Peripheral membrane protein. Cytoplasmic side. Cytoplasm. Secretory vesicle. Synaptosome.
- Tissue details: Detected in pancreas islets (at protein level). Detected in brain and pancreas.
- Research category: Signal Transduction
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
