| Field | Specification |
|---|---|
| Target | |
| Alternative names | Cyclin-dependent kinase 4 inhibitor D;p19-INK4d;Cdkn2d; |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Recombinant human p19INK4d. |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone DCS-100 is a mouse monoclonal antibody that recognizes cyclin-dependent kinase 4 inhibitor D (gene Cdkn2d) in human samples and is validated for Western blot, IHC and ICC/IF.
p19INK4d (CDKN2D) is an INK4 family cyclin-dependent kinase inhibitor that binds CDK4 and CDK6 and blocks their activity. By restraining G1 progression it helps control cell proliferation, and it is studied in cell cycle regulation and differentiation.
| Target | Cyclin-dependent kinase 4 inhibitor D (gene Cdkn2d; UniProt Q60773, mouse) |
|---|---|
| Clone | DCS-100 |
| Host / Clonality / Isotype | Mouse / Monoclonal / Mouse IgG1 |
| Reactivity | Human |
| Purification | Ascites |
| Form | Lyophilized |
| Formulation | 1.2% sodium acetate; 0.01 mg NaN3; plus stabilizers |
| Reconstitution | 100 µg/mL after adding 1 mL PBS |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| IHC (paraffin sections) | 1–2 µg/mL (Human) |
|---|---|
| Western blot | 0.5–1 µg/mL (Human) |
| Immunocytochemistry / Immunofluorescence | Not specified by the supplier |
Immunogen
Recombinant human p19INK4d.
Reactivity Notes
The supplier lists reactivity with human. UniProt places cyclin-dependent kinase 4 inhibitor D in the nucleus and cytoplasm.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
Xingsheng Hu et al. (2024) The expression and role of SUZ12 in lung adenocarcinoma. Cancer Medicine. 10.1002/cam4.70190