| Field | Specification |
|---|---|
| Target | |
| Alternative names | Paxillin;Pxn; |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | C-terminal part of recombinant chicken paxillin (amino acids 305-559). |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone PXC-10 is a mouse monoclonal antibody that recognizes paxillin (gene Pxn) in bovine, chicken, hamster, human, mouse and rat samples and is validated for Western blot and ICC/IF.
Paxillin (PXN) is a focal adhesion adaptor protein that links integrin-based adhesions to the actin cytoskeleton. It is phosphorylated by FAK and Src and serves as a docking site for many signaling and structural proteins, so it is widely used as a marker in studies of cell adhesion and migration.
| Target | Paxillin (gene Pxn; UniProt Q66H76, rat) |
|---|---|
| Clone | PXC-10 |
| Host / Clonality / Isotype | Mouse / Monoclonal / Mouse IgG1 |
| Reactivity | Bovine, Chicken, Hamster, Human, Mouse, Rat |
| Purification | Ascites |
| Form | Lyophilized |
| Formulation | 1.2% sodium acetate; 0.01 mg NaN3; plus stabilizers |
| Reconstitution | 100 µg/mL after adding 1 mL PBS |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1–2 µg/mL (Human, Mouse, Rat, Chicken) |
|---|---|
| Immunocytochemistry / Immunofluorescence | Not specified by the supplier |
Immunogen
C-terminal part of recombinant chicken paxillin (amino acids 305–559).
Reactivity Notes
The supplier lists reactivity with bovine, chicken, hamster, human, mouse and rat. UniProt places paxillin in the cytoplasm and cell junction.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.