| Field | Specification |
|---|---|
| Target | |
| Alternative names | Prostaglandin E2 receptor EP2 subtype;PGE receptor EP2 subtype;PGE2 receptor EP2 subtype;Prostanoid EP2 receptor;PTGER2; |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human PTGER2, different from the related mouse sequence by four amino acids, and from the related rat sequence by three amino acids. |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody recognizes prostaglandin E2 receptor EP2 subtype (gene PTGER2) in human samples and is validated for Western blot. The predicted molecular weight is 39.8 kDa, and the supplier reports an observed band at about 40 kDa.
The EP2 receptor (PTGER2) is a Gs-coupled receptor for prostaglandin E2 that raises intracellular cAMP. It relaxes smooth muscle and modulates inflammation, immune cell function and reproduction, making it a subject of research on inflammatory signaling and neuroinflammation.
| Target | Prostaglandin E2 receptor EP2 subtype (gene PTGER2; UniProt P43116, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / Rabbit IgG |
| Reactivity | Human |
| Form | Lyophilized |
| Formulation | Per vial: 0.9 mg NaCl; 0.2 mg Na2HPO4; 0.05 mg NaN3; plus stabilizers |
| Calculated MW | 39.8 kDa |
| Observed MW | 40 kDa |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 0.1–0.5 µg/mL (Human) |
|---|
Samples with a confirmed band (WB): human placenta tissue, A549 cells, HepG2 cells.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide from the C-terminal region of human PTGER2. It differs from the mouse sequence at four residues and from the rat sequence at three residues.
Reactivity Notes
The supplier lists reactivity with human. UniProt places prostaglandin E2 receptor EP2 subtype in the cell membrane. Tissue expression noted by UniProt (human): Placenta and lung. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
