| Field | Specification |
|---|---|
| Target | |
| Alternative names | Prospero homeobox protein 1;Homeobox prospero-like protein PROX1;PROX-1;PROX1; |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human PROX1 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone ABCO-16 is a rabbit monoclonal antibody that recognizes prospero homeobox protein 1 (gene PROX1) in human samples and is validated for Western blot. The predicted molecular weight is 83.2 kDa, and the supplier reports an observed band at about 95 kDa.
PROX1 is a homeobox transcription factor related to Drosophila Prospero. It is the key fate determinant of lymphatic endothelial cells and is also required for development of the lens, liver, heart and parts of the nervous system, so PROX1 is widely used as a lymphatic endothelial marker and studied in organogenesis.
| Target | Prospero homeobox protein 1 (gene PROX1; UniProt Q92786, human) |
|---|---|
| Clone | ABCO-16 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 83.2 kDa |
| Observed MW | 95 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|
Samples with a confirmed band (WB): HepG2 cells.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of human PROX1.
Reactivity Notes
The supplier lists reactivity with human. UniProt places prospero homeobox protein 1 in the nucleus. Tissue expression noted by UniProt (human): Most actively expressed in the developing lens. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
