| Field | Specification |
|---|---|
| Target | |
| Alternative names | Prostate tumor-overexpressed gene 1 protein;PTOV-1;Activator interaction domain-containing protein 2;PTOV1;ACID2;PP642, UNQ6127/PRO20092; |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human PTOV1, different from the related mouse and rat sequences by one amino acid. |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody recognizes prostate tumor-overexpressed gene 1 protein (gene PTOV1) in human and rat samples and is validated for Western blot. The predicted molecular weight is 46.9 kDa, and the supplier reports an observed band at about 47 kDa.
PTOV1 (prostate tumor-overexpressed gene 1) was first identified as a protein highly expressed in prostate cancer. It is reported to support transcription, to be needed for nuclear entry of flotillin-1 and to promote cell proliferation, though its mechanisms are not fully defined.
| Target | Prostate tumor-overexpressed gene 1 protein (gene PTOV1; UniProt Q86YD1, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / Rabbit IgG |
| Reactivity | Human, Rat |
| Form | Lyophilized |
| Formulation | Per vial: 0.9 mg NaCl; 0.2 mg Na2HPO4; 0.05 mg NaN3; plus stabilizers |
| Calculated MW | 46.9 kDa |
| Observed MW | 47 kDa |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 0.1–0.5 µg/mL (Rat, Human) |
|---|
Samples with a confirmed band (WB): rat brain tissue, rat kidney tissue.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide from the C-terminal region of human PTOV1. It differs from the mouse and rat sequences at one residue.
Reactivity Notes
The supplier lists reactivity with human and rat. UniProt places prostate tumor-overexpressed gene 1 protein in the cytoplasm, nucleus and cell membrane. Tissue expression noted by UniProt (human): Expressed in brain, heart, kidney, liver, placenta, skeletal muscle and small intestine. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
