| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Ras-related protein Rab-3C;RAB3C; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Gene ID | |
| Host | |
| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human Rab3C, different from the related mouse and rat sequences by one amino acid. |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Overview
Anti-Ras-related protein Rab-3C Rab3C Antibody Picoband® is an antibody targeting RAB3C. Common applications include WB, IHC, Flow Cytometry, ELISA. Key specifications include host: Rabbit; clonality: Polyclonal; isotype: Rabbit IgG; reactivity: Human,Mouse,Rat; observed MW: 26 kDa; calculated MW: 25952 MW.
Boster Bio Anti-Ras-related protein Rab-3C Rab3C Antibody catalog # PA2279. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key elements and design rationale
- Target: RAB3C — Ras-related protein Rab-3C
- Antibody format: Host: Rabbit; Clonality: Polyclonal; Isotype: Rabbit IgG
- Species reactivity: Human,Mouse,Rat
- Molecular weight guidance: Observed: 26 kDa; Calculated: 25952 MW
Specificity note: No cross reactivity with other proteins.
Biological background
Protein function (datasheet): Protein transport. Probably involved in vesicular traffic (By similarity). .
Scientific background (datasheet): Ras-related protein Rab-3C is a protein that in humans is encoded by the RAB3C gene. It is mapped to 5q11.2. RAB3C is found in brain, adrenal gland and pituitary. This gene is one of the small GTPases implicated in the regulation of vesicular trafficking between membrane compartments. RAB3C gene contains 6 exons and spans more than 310 kb. The function of this gene is transporting protein, and probably involved in vesicular traffic. RAB3C can interact with RIMS2, RPH3A and RPH3AL.
Cellular localization (datasheet): Cell membrane ; Lipid-anchor ; Cytoplasmic side .
Tissue details (datasheet): Expressed in brain, placenta and lung. .
Sequence similarities (datasheet): Belongs to the beta-catenin family.
Research relevance and current trends
- Commonly studied in contexts related to G Protein Signaling,Protein Trafficking,Ras Family,Signal Transduction,Signaling Pathway,Small G Proteins,Vesicle Transport.
- Supports comparative expression analysis across conditions, genotypes, or treatments when paired with appropriate controls.
- Useful for confirming target presence and subcellular distribution using orthogonal readouts (e.g., microscopy vs. immunoblotting).
Common research applications
- Western blot (WB): Compare relative target abundance and apparent size/isoforms across samples; interpret bands in light of expected MW and potential PTMs.
- ELISA: Measure target abundance in compatible matrices using a standard-curve readout; ensure dilution linearity and appropriate controls.
- Immunohistochemistry (IHC): Assess tissue distribution and cell-type patterns; interpret staining with appropriate negative controls and antigen context.
- Flow cytometry: Quantify target-positive populations in single-cell suspensions; pair with viability and isotype/FMO controls conceptually.
Notes for experimental interpretation
- Consider isoforms, post-translational modifications, and processing that can shift apparent molecular weight or localization.
- Cross-reactivity (datasheet): No cross-reactivity with other proteins
- Use appropriate positive and negative controls (e.g., KO/KD, blocking peptide, or isotype controls) to support specificity interpretation.
As a polyclonal antibody, this reagent may recognize multiple epitopes on the target, which can improve detection robustness but may require careful specificity controls.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
