| Field | Specification |
|---|---|
| Target | |
| Alternative names | Nuclear receptor ROR-beta; Nuclear receptor RZR-beta; Nuclear receptor subfamily 1 group F member 2; Retinoid-related orphan receptor-beta; RORB; NR1F2; RZRB |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human ROR beta |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 22R66 is a rabbit monoclonal antibody that recognizes nuclear receptor ROR-beta (gene RORB) in human and mouse samples and is validated for Western blot. The predicted molecular weight is 53.2 kDa, and the supplier reports an observed band at about 53 kDa.
RORβ (RORB) is a nuclear receptor that binds ROR response elements as a monomer to control gene expression. It is expressed in the retina, brain regions such as the thalamus and cortex layer 4, and the pineal gland, and it is needed for normal photoreceptor development and has been linked to circadian rhythm regulation.
| Target | Nuclear receptor ROR-beta (gene RORB; UniProt Q92753, human) |
|---|---|
| Clone | 22R66 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human, Mouse |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 53.2 kDa |
| Observed MW | 53 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|
Immunogen
Synthetic peptide based on the sequence of human ROR beta.
Reactivity Notes
The supplier lists reactivity with human and mouse. UniProt places nuclear receptor ROR-beta in the nucleus.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
Tao Gong et al. (2015) Inhibition of Tumor Growth and Immunomodulatory Effects of Flavonoids and Scutebarbatines of Scutellaria barbata D. Don in Lewis-Bearing C57BL/6 Mice. Evidence-based Complementary and Alternative Medicine. 10.1155/2015/630760
