| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Protein S100-A10;Calpactin I light chain;Calpactin-1 light chain;Cellular ligand of annexin II;S100 calcium-binding protein A10;p10 protein;p11;S100A10;ANX2LG, CAL1L, CLP11; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Form | Liquid |
| Host | |
| Immunogen | A synthesized peptide derived from human S100A10 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Storage | |
| Target | |
| UniProt # |
Overview
This product is an anti-S100A10 antibody for target detection and characterization. Key identifiers include host species: Rabbit; Monoclonal; clone AODO-19; isotype Rabbit IgG; reactivity: Human,Mouse. Reported application contexts include WB, IHC (as provided in the source record). Boster Bio Anti-S100A10 Rabbit Monoclonal Antibody catalog # M02787. Tested in WB, IHC applications. This antibody reacts with Human, Mouse.
Key elements and design rationale
- Target: S100A10 (Protein S100-A10).
- Antibody format: Monoclonal; clone AODO-19; isotype Rabbit IgG.
- Host: Rabbit.
- Species reactivity: Human,Mouse (confirm in your model system with appropriate controls).
This description is intended to help interpret the antibody design and the biological context of the target using the fields provided in the catalog record, alongside general experimental considerations.
Biological background
S100A10 (protein: T-cell surface glycoprotein CD3 zeta chain) is a commonly studied target in molecular and cellular biology. Functional context (as provided): Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine- specific kinase. Reported cellular localization context: Cytoplasm. Tissue expression notes (as provided): Widely expressed.
Research relevance and current trends
- Research context keywords from the source record include: Calcium Binding Proteins,Calcium Signaling,Cell Adhesion,Cytoskeleton/ECM,Signal Transduction,Signaling Pathway.
- Current studies often focus on connecting target abundance/localization to pathway perturbations across models, tissues, and cell states.
- Quantitative and multiplexed assays (e.g., imaging + immunoblot panels) are commonly used to compare phenotypes across conditions and time-courses.
Common research applications
- Western blotting (WB): assess relative target abundance across samples, treatments, or time-points.
- Immunohistochemistry (IHC): evaluate spatial distribution of target-positive staining in tissue architecture.
Workflow ideas (metafield): Validate S100A10 antibody specificity using KO/KD control samples (WB/IF/IHC as appropriate), Detect S100A10 expression by Western blot in cell or tissue lysates, Detect S100A10 in FFPE tissue sections by immunohistochemistry
Notes for experimental interpretation
- Consider isoforms and post-translational modifications (PTMs) that may shift apparent molecular weight or epitope accessibility.
- Apparent molecular weight may vary by sample type and processing (observed MW: 70 kDa, 90 kDa; calculated MW: 11203 MW).
- Control concepts: include appropriate negative controls (e.g., isotype, KO/KD samples) and orthogonal validation when feasible.
Additional product details (from the source record)
- Molecular weight (observed): 70 kDa, 90 kDa
- Cellular localization (provided): Cytoplasm.
- Tissue details (provided): Widely expressed.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
