| Field | Specification |
|---|---|
| Target | |
| Alternative names | Somatostatin receptor type 1;SS-1-R;SS1-R;SS1R;SRIF-2;SSTR1; |
| Gene ID | |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human Somatostatin Receptor 1, identical to the related rat and mouse sequences. |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody recognizes somatostatin receptor type 1 (gene SSTR1) in human, mouse and rat samples and is validated for Western blot and IHC. The predicted molecular weight is 42.7 kDa, and the supplier reports an observed band at about 60 kDa.
Somatostatin receptor 1 (SSTR1) is a G protein-coupled receptor that binds somatostatin, preferring the 14-amino-acid form over somatostatin-28. Through inhibitory G proteins it lowers adenylyl cyclase activity, and it can also stimulate a phosphotyrosine phosphatase and the Na+/H+ exchanger, linking somatostatin signaling to cell growth control.
| Target | Somatostatin receptor type 1 (gene SSTR1; UniProt P30872, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / Rabbit IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Lyophilized |
| Formulation | Per vial: 0.9 mg NaCl; 0.2 mg Na2HPO4; 0.05 mg thimerosal; 0.05 mg NaN3; plus stabilizers |
| Calculated MW | 42.7 kDa |
| Observed MW | 60 kDa |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| IHC (paraffin sections) | 0.5–1 µg/mL (Rat, Human, Mouse) |
|---|---|
| Western blot | 0.1–0.5 µg/mL (Rat, Human, Mouse) |
Samples with a confirmed band (WB): rat intestine tissue.
Recommended loading (WB): 20–40 µg of total protein per lane.
Samples with confirmed staining (IHC): rat intestine tissue.
Recommended antigen retrieval: heat-mediated, in TE buffer (pH 9.0); citrate buffer (pH 6.0) can be used instead.
Immunogen
Synthetic peptide from the C-terminal region of human somatostatin Receptor 1. The peptide sequence is conserved in rat and mouse.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places somatostatin receptor type 1 in the cell membrane. Tissue expression noted by UniProt (human): Fetal kidney, fetal liver, and adult pancreas, brain, lung, jejunum and stomach. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
Yan Xie et al. (2011) SOM230 combined with celecoxib prolongs the survival in nude mice with HepG-2 xenografts. Cancer Biology & Therapy. 10.4161/cbt.12.1.15730
Yanhua Zhao et al. (2018) Expression of somatostatin and its receptor 1‑5 in endometriotic tissues and cells. Experimental and Therapeutic Medicine. 10.3892/etm.2018.6730
