| Field | Specification |
|---|---|
| Target | |
| Alternative names | Transcription factor SOX-10;SOX10; |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human SOX10 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone GIE-19 is a rabbit monoclonal antibody that recognizes transcription factor SOX-10 (gene SOX10) in human samples and is validated for Western blot and IHC. The predicted molecular weight is 49.9 kDa, and the supplier reports an observed band at about 70 kDa.
Transcription factor SOX-10 (SOX10) is an HMG-box transcription factor central to neural crest derivatives and glial cells. It drives the myelination program in oligodendrocytes, including induction of MYRF and myelin genes, and together with PAX3 activates MITF in melanocytes, so SOX10 is a widely used marker for oligodendrocytes, Schwann cells and melanocytic cells.
| Target | Transcription factor SOX-10 (gene SOX10; UniProt P56693, human) |
|---|---|
| Clone | GIE-19 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 49.9 kDa |
| Observed MW | 70 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:1000–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
Samples with confirmed staining (IHC): human breast tissue.
Recommended antigen retrieval: heat-mediated, in TE buffer (pH 9.0); citrate buffer (pH 6.0) can be used instead.
Immunogen
Synthetic peptide based on the sequence of human SOX10.
Reactivity Notes
The supplier lists reactivity with human. UniProt places transcription factor SOX-10 in the cytoplasm, nucleus and mitochondrion outer membrane. Tissue expression noted by UniProt (human): Expressed in fetal brain and in adult brain, heart, small intestine and colon. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
