| Field | Specification |
|---|---|
| Target | |
| Alternative names | Stanniocalcin-1; STC-1; STC1; STC |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | E.coli-derived human Stanniocalcin 1/STC/STC1 recombinant protein (Position: V34-A247). |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody recognizes stanniocalcin-1 (gene STC1) in human samples and is validated for IHC and ELISA. The predicted molecular weight is 27.6 kDa.
Stanniocalcin-1 (STC1) is a secreted glycoprotein hormone first identified in fish, where it controls calcium balance. In mammals it is expressed in many tissues and influences phosphate reabsorption in the kidney, and it is studied in calcium and phosphate homeostasis, stress responses and cancer.
| Target | Stanniocalcin-1 (gene STC1; UniProt P52823, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / Rabbit IgG |
| Reactivity | Human |
| Form | Lyophilized |
| Formulation | Per vial: 4 mg trehalose; 0.9 mg NaCl; 0.2 mg Na2HPO4 |
| Calculated MW | 27.6 kDa |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| IHC (paraffin sections) | 2–5 µg/mL (Human) |
|---|---|
| ELISA | 0.1–0.5 µg/mL |
Samples with confirmed staining (IHC): human intestinal cancer tissue.
Recommended antigen retrieval: heat-mediated, in TE buffer (pH 9.0); citrate buffer (pH 6.0) can be used instead.
Conditions in the example images (IHC): heat-mediated antigen retrieval in EDTA buffer (pH 8.0).
Immunogen
Recombinant human Stanniocalcin 1/STC/STC1 fragment (Val34–Ala247), expressed in E. coli.
Reactivity Notes
The supplier lists reactivity with human. UniProt describes stanniocalcin-1 as a secreted protein. Tissue expression noted by UniProt (human): Expressed in most tissues, with the highest levels in ovary, prostate, heart, kidney and thyroid.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
Yong Li et al. (2017) Stanniocalcin-1 augments stem-like traits of glioblastoma cells through binding and activating NOTCH1. Cancer Letters. 10.1016/j.canlet.2017.11.033
