| Field | Specification |
|---|---|
| Target | |
| Alternative names | Synaptophysin;Major synaptic vesicle protein p38;Syp; |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Rat retina synaptosome. |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone SVP-38 is a mouse monoclonal antibody that recognizes synaptophysin (gene Syp) in human and rat samples and is validated for Western blot and IHC.
Synaptophysin (SYP) is an abundant integral membrane glycoprotein of synaptic vesicles in neurons and neuroendocrine cells. It interacts with synaptobrevin and is involved in vesicle organization and synaptic plasticity, and it is one of the most widely used markers for synapses and neuroendocrine tissue.
| Target | Synaptophysin (gene Syp; UniProt P07825, rat) |
|---|---|
| Clone | SVP-38 |
| Host / Clonality / Isotype | Mouse / Monoclonal / Mouse IgG1 |
| Reactivity | Human, Rat |
| Purification | Ascites |
| Form | Lyophilized |
| Formulation | 1.2% sodium acetate; 0.01 mg NaN3; plus stabilizers |
| Reconstitution | 100 µg/mL after adding 1 mL PBS |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| IHC (paraffin sections) | 1–2 µg/mL (Human, Rat) |
|---|---|
| Western blot | 0.5–1 µg/mL (Human, Rat) |
Immunogen
Rat retina synaptosome.
Reactivity Notes
The supplier lists reactivity with human and rat. UniProt places synaptophysin in the synapse. Tissue expression noted by UniProt (rat): Expressed in the brain with expression in the cerebrum and the cerebellum.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
Ling Tian et al. (2024) Increased Thyroid Hormone Action Alleviates Hippocampal Damage by Downregulating Neuronal Type I Interferon Signaling/Necroptosis in Diabetes-Associated Cognitive Dysfunction. Thyroid. 10.1089/thy.2024.0087
Keming Yu et al. (2008) TSP-1 Secreted by Bone Marrow Stromal Cells Contributes to Retinal Ganglion Cell Neurite Outgrowth and Survival. PLoS One. 10.1371/journal.pone.0002470
