| Field | Specification |
|---|---|
| Target | |
| Alternative names | Tumor necrosis factor receptor superfamily member 13B; Transmembrane activator and CAML interactor; CD267; TNFRSF13B; TACI |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | E. coli-derived human TACI recombinant protein (Position: M1-S165). |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody targets tumor necrosis factor receptor superfamily member 13B (gene TNFRSF13B) in human samples and is validated for IHC. The predicted molecular weight is 31.8 kDa.
TACI (TNFRSF13B) is a receptor for the B-cell cytokines BAFF and APRIL. Expressed on B cells, it activates NF-AT, NF-κB and AP-1 and helps regulate antibody production, class switching and plasma cell differentiation. TACI variants are associated with common variable immunodeficiency, and it is studied in B-cell biology and autoimmunity.
| Target | Tumor necrosis factor receptor superfamily member 13B (gene TNFRSF13B; UniProt O14836, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / Rabbit IgG |
| Reactivity | Human |
| Form | Lyophilized |
| Formulation | Per vial: 4 mg trehalose; 0.9 mg NaCl; 0.2 mg Na2HPO4 |
| Calculated MW | 31.8 kDa |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| IHC (paraffin sections) | 2–5 µg/mL |
|---|
Samples with confirmed staining (IHC): human breast cancer tissue, human cervical cancer tissue, human colorectal adenocarcinoma tissue, human spleen tissue.
Recommended antigen retrieval: heat-mediated, in TE buffer (pH 9.0); citrate buffer (pH 6.0) can be used instead.
Conditions in the example images (IHC): heat-mediated antigen retrieval in EDTA buffer (pH 8.0).
Immunogen
Recombinant human TACI fragment (Met1–Ser165), expressed in E. coli.
Reactivity Notes
The supplier lists reactivity with human. UniProt places tumor necrosis factor receptor superfamily member 13B in the membrane. Tissue expression noted by UniProt (human): Highly expressed in spleen, thymus, small intestine and peripheral blood leukocytes.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.