| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | Hemihydrate; R-(-)-6ab-aporphine-10,11-diol, hydrochloride; (R)-5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol, hydrochloride |
| Cas No. | |
| Form | Gray Powder |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | May be dissolved in water (20 mg/ml) |
| Source | Synthetic |
| Storage |
Apomorphine HCl Hydrate is a non-selective dopamine receptor agonist with established clinical use in Parkinson’s disease. It exhibits neuroprotective effects in preclinical models, including protection against MPTP-induced neurotoxicity. Apomorphine is used to manage motor fluctuations in Parkinson’s patients and serves as a model compound for studying dopaminergic signaling, neurodegeneration, and therapeutic interventions targeting dopamine pathways.
Classification: Danger.
Hazard Statements:
H301
Precautionary Statements:
P301 + P310 + P330
Apomorphine HCl Hydrate (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-619)
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- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
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2.Millan M.J., et al. (2002) J. Pharmacol. Exp. Ther. 303:791.
3. Grunblatt E., et al. (1999) Mov. Disord. 1999 14:612.
4. Auffret M., et al.( 2017) J. Neurol. Sci. 372:279.
5. Jenner P.and R Katzenschlager ( 2016) Parkinsonism. Relat. Disord. 33 Suppl 1:S13.