| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | ACT-132577 |
| Cas No. | |
| Molecular Weight | |
| Product Type | |
| Signaling Pathway | |
| SMILES | |
| Target |
Compound Overview
Aprocitentan (CAS 1103522-45-7) is a research-grade small molecule supplied by TargetMol.
Alternative names: ACT-132577
Physical Properties
| CAS Number | 1103522-45-7 |
|---|---|
| Molecular Formula | C16H14Br2N6O4S |
| Molecular Weight | 546.19 g/mol |
| SMILES | O(CCOC=1N=CC(Br)=CN1)C=2C(=C(NS(N)(=O)=O)N=CN2)C3=CC=C(Br)C=C3 |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
Aprocitentan (ACT-132577) is ETA and ETB antagonist .
Target(s): Endothelin Receptor
Signaling pathway(s): GPCR/G Protein
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
Use a bath-type ultrasonic cleaner at standard cleaning frequency (37–40 kHz). Bath sonication is gentler than a probe sonicator and avoids sample overheating. Sonicate in 5–10 second intervals, checking solubility between pulses, for no more than 2–3 minutes total. Warm the bath to 37 °C if solubility remains poor.
For currently available products, batch-specific purity data (HPLC chromatogram, NMR spectrum, and Certificate of Analysis) is accessible via the DataSheet link on the product page. For future or custom synthesis products, purity determination is conducted upon availability and published on the product page. Contact BioHippo for batch-specific CoA requests or custom synthesis enquiries.
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- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
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