| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone; OPC-14597 |
| Cas No. | |
| Form | White powder |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | May be dissolved in DMSO (30 mg/ml); or ethanol (5 mg/ml, warm) |
| Source | Synthetic |
| Storage |
Aripiprazole is an atypical antipsychotic with a unique pharmacological profile, acting as a partial agonist at dopamine D2 receptors and serotonin 5-HT1A receptors, and as an antagonist at 5-HT2A receptors. It is clinically used to treat schizophrenia and bipolar disorder and has shown efficacy in managing psychosis in Alzheimer’s disease. Aripiprazole also modulates reward pathways and has been shown to reduce drug-seeking behavior in animal models. Its dopaminergic and serotonergic modulation makes it relevant in neuropsychiatric and neurodegenerative research.
Classification: Danger
GHS Hazard Statements
H301 (62.7%): Toxic if swallowed [Danger Acute toxicity, oral]
H302 (35.3%): Harmful if swallowed [Warning Acute toxicity, oral]
H361 (15.7%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]
H413 (13.7%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard]
Precautionary Statement Codes:
P203, P264, P270, P273, P280, P301+P316, P301+P317, P318, P321, P330, P405, and P501
Aripiprazole (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-630)
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2. T Kikuchi et al. J. Pharmacol. Exp. Ther. 1995 274:329
3. S Madhusoodanan et al. Clin. Interv. Aging. 2008 3:491
4. MW Feltenstein et al. Biol. Psychiatry 2007 61:582