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| Target |
Compound Overview
ASK1-IN-4 (CAS 1427538-26-8) is a research-grade small molecule supplied by TargetMol.
Physical Properties
| CAS Number | 1427538-26-8 |
|---|---|
| Molecular Formula | C18H14BrNO4S2 |
| Molecular Weight | 452.34 g/mol |
| SMILES | C(C=1OC(=CC1)C2=CC=C(Br)C=C2)=C3/C(=O)N(CCCC(O)=O)C(=S)S3 |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
ASK1-IN-4 is an ASK1 inhibitor, IC50 = 0.2 uM.
Target(s): ASK
Signaling pathway(s): Apoptosis
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
The concentration of stock solution should be lower than the solubility provided on the official website. Within this range, the concentration of stock solution should be set based on that of working solution. For cell experiments, it is recommended to set the stock solution concentration at least 1000 times higher than that of working solution.
If you are using DMSO for preparation,sterilization is not recommended, as DMSO itself possesses strong sterilizing properties. The prepared solution is sterile. For further assurance, it can be left overnight at 4°C. The safest method is to filter through a specialized organic filter membrane. If water is used for preparation,sterilization can be achieved by filtering through a 0.22 μm filter membrane.
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- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
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- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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