| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | AG-013736, N-Methyl-2-((3-((1E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide, N-Methyl-[[3[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-benzamide |
| Cas No. | |
| Form | White to tan powder |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble to 25 mM in DMSO |
| Source | Synthetic |
| Storage |
Axitinib is a potent and selective tyrosine kinase inhibitor that targets VEGF receptors 1, 2, and 3. It also inhibits PDGFR-β and c-Kit. In neuroscience, Axitinib is used to study angiogenesis, blood-brain barrier function, and neurovascular remodeling. Its anti-angiogenic properties make it a valuable tool for investigating the vascular contributions to neurodegenerative diseases and brain tumors.
Classification: Acute toxicity, Oral (Category 4), H302
Acute aquatic toxicity (Category 1), H400
Chronic aquatic toxicity (Category 1), H410
Safety Phrases:
- S22 - Do not breathe dust.
- S24/25 - Avoid contact with skin and eyes.
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Hazard statements:
- H302 Harmful if swallowed.
- H410 Very toxic to aquatic life with long lasting effects
Precautionary statements:
- P264 Wash skin thoroughly after handling.
- P270 Do not eat, drink or smoke when using this product.
- P273 Avoid release to the environment.
- P301 + P312 IF SWALLOWED: Call a POISON CENTER or doctor/ physician if you feel unwell.
- P330 Rinse mouth.
- P391 Collect spillage.
- P501 Dispose of contents/ container to an approved waste disposal plant.
Axitinib (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-494)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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equivalents, or discuss custom synthesis with the right QC documentation (RUO).
