AZ31

SKU:BHB20410313
Overview
Click light‑blue chips for details
AZ31 (CAS 2088113-98-6) is a kinase inhibitor supplied as a solid powder by TargetMol. For biochemical profiling and cell-based assay applications.
Activity Kinase Inhibitor
CAS No. 2088113-98-6
Molecular Weight 420.50 g/mol
Form Solid
Shipping Room Temperature
Options selector
Catalog no. Size
T19671-2MG 2 mg
T19671-5MG 5 mg
T19671-1MLX10MM 1 mL x 10 mM (in DMSO)
T19671-10MG 10 mg
T19671-25MG 25 mg
T19671-50MG 50 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 2 mg, 5 mg, 1 mL x 10 mM (in DMSO), 10 mg, 25 mg, 50 mg
  • Lead time: In Stock at Manufacturer — options listed in "Availability Content"; other statuses may take longer.
  • Storage: −20 °C
  • Shipping: Room temperature (RT) shipment.
  • Upon receipt: Store at −20 °C as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No T19671
Activity
  • Kinase Inhibitor
Alternative Names AZ 31
Cas No. 2088113-98-6
Molecular Weight 420.5
Product Type
  • Small Molecule Inhibitor
Signaling Pathway DNA Damage/DNA Repair///PI3K/Akt/mTOR signaling
SMILES N((CH)(C)C1CCOCC1)C=2C3=C(N=CC2C(N)=O)C=CC(=C3)C=4C=CC(COC)=NC4
Target ATM/ATR

Compound Overview

AZ31 (CAS 2088113-98-6) is a research-grade small molecule supplied by TargetMol.

Alternative names: AZ 31

Physical Properties

CAS Number 2088113-98-6
Molecular Formula C24H28N4O3
Molecular Weight 420.50 g/mol
SMILES N((CH)(C)C1CCOCC1)C=2C3=C(N=CC2C(N)=O)C=CC(=C3)C=4C=CC(COC)=NC4
Form Solid
Shipping Room Temperature (RT)

Biological Activity

AZ31 is an ATM inhibitor with potency, high selectivity, and oral activity.AZ31 inhibits ATM enzymes, intracellular ATM, with IC50 values of <1.2 nM and 46 nM, respectively.AZ31 exhibits excellent ATR selectivity, PIKK family selectivity, and pan-kinase selectivity.AZ31 is a potent in vitro radiosensitizer that can be used for cancer research.

Target(s): ATM/ATR

Signaling pathway(s): DNA Damage/DNA Repair, PI3K/Akt/mTOR signaling

Safety & Regulatory

For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.

Whether sonication is needed for product dissolution? What if I don't have an ultrasound machine?

sonication can accelerate dissolution. If the compound is not dissolving, sonication is recommended. If you don't have an ultrasound machine, a lower solvent concentration or using less powder are recommended.

How to set the concentration of stock solution?

The concentration of stock solution should be lower than the solubility provided on the official website. Within this range, the concentration of stock solution should be set based on that of working solution. For cell experiments, it is recommended to set the stock solution concentration at least 1000 times higher than that of working solution.

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

Matches this product
15%OFF
15% Off Cancer Antibodies
Ends Sep 30 ONCO15
$50 OFF
$50 Off All ELISA Kits
Limited time ELISA50
10% OFF
10% OFF CELL LINES-Limited-Time Offer
Ends Sep 30 CELL10
FREE SAMPLE
Free Sample – CellTrypase Recombinant Trypsin-Like Enzyme
Limited time offer – availa... FREESAMPLE
FREE SAMPLE
Free Sample – MycoFold™ Growth Factors
Limited time offer – availa... Request Free Sample

Get a Quote

Please use this form for bulk quantity requests or customized products.

Contact Information

Product Information

Try Celltrypse Free – Request Your Sample Today

Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

Try Celltrypse Free – Request Your Sample Today

Try Celltrypse Free – Request Your Sample Today

Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

Try Celltrypse Free – Request Your Sample Today