| Field | Specification |
|---|---|
| Mfr No | |
| Clonality | |
| Host | |
| Immunogen | A recombinant fragment of human ICOSLG/B7RP-1 protein (within amino acids 1-300) was used as the immunogen for the B7RP-1 antibody. |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage | |
| Target | |
| UniProt # |
Overview
B7RP-1 Antibody / ICOSLG is an antibody targeting B7RP-1. Host: Mouse. Monoclonal. Clone: ICOSL/7700. Format: Purified. Applications: IHC-P.
Key elements and design rationale
- Target: B7RP-1.
- Immunogen: A recombinant fragment of human ICOSLG/B7RP-1 protein (within amino acids 1-300) was used as the immunogen for the B7RP….
- Species reactivity: Human.
- Localization: Cell Surface, Cytoplasm.
- Conjugate: Unconjugated (no label listed).
Biological background (from provided description)
This mAb recognizes a protein of 36kDa, identified as ICOS-L, also called B7RP-1 or B7-related protein 1. It is a ligand for the ICOS receptor that initiates T and B cell proliferation and cytokine secretion. ICOS-L interactions play an essential role in T cell-dependent B cell activation in peripheral lymphoid organs such as spleen and lymph nodes.
Common research applications
- IHC: tissue distribution assessment; interpret with matched controls.
Notes for experimental interpretation
- Account for isoforms, paralogs, and post-translational modifications when interpreting signal.
- Support specificity with biological controls (e.g., KO/KD where available) and technical controls (e.g., secondary-only/isotype).
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
