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Compound Overview
BDM91270 (CAS 2892824-11-0) is a research-grade small molecule supplied by TargetMol.
Physical Properties
| CAS Number | 2892824-11-0 |
|---|---|
| Molecular Formula | C17H21Cl3N4O2 |
| Molecular Weight | 419.73 g/mol |
| SMILES | O=C(C1=CN=C(N2CCNCC2)C(Cl)=C1)OC3=CC=CC(CN)=C3.Cl.Cl |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
BDM91270 (compound 29) serves as an inhibitor of the E. coli AcrAB-TolC efflux pump, displaying an EC90 value of 0.6 uM against wild-type E. coli AcrB. It has applications in research on Escherichia coli drug resistance (1).
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
When solubility is listed as < 1 mg/mL, the compound dissolves to less than 1 mg per milliliter in water at 25 °C, pH 7.4. Such compounds require an organic co-solvent such as DMSO to prepare a concentrated stock, which is then diluted into aqueous assay buffer. For cell-based assays, keep the final DMSO concentration below 0.1% (v/v) to avoid solvent-induced cytotoxicity.
mg/mL (milligrams per milliliter) and mM (millimolar = millimoles per liter) are two concentration units for the same solution. To convert: mM = (mg/mL × 1000) / MW (g/mol). For example, for a compound with MW = 350 g/mol: 1 mg/mL = 1000/350 = 2.86 mM. Use the molar concentration calculator on the TargetMol website for quick conversions.
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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