BEBT-109

SKU:BHB20444332
Overview
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BEBT-109 (CAS 2050906-40-4) is a kinase inhibitor supplied as a solid powder by TargetMol. For biochemical profiling and cell-based assay applications.
Activity Kinase Inhibitor
CAS No. 2050906-40-4
Molecular Weight 516.59 g/mol
Form Solid
Shipping Room Temperature
Options selector
Catalog no. Size
T80643-1MG 1 mg
T80643-5MG 5 mg
T80643-1MLX10MM 1 mL x 10 mM (in DMSO)
T80643-10MG 10 mg
T80643-25MG 25 mg
T80643-50MG 50 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 1 mg, 5 mg, 1 mL x 10 mM (in DMSO), 10 mg, 25 mg, 50 mg
  • Lead time: In Stock at Manufacturer — options listed in "Availability Content"; other statuses may take longer.
  • Storage: −20 °C
  • Shipping: Room temperature (RT) shipment.
  • Upon receipt: Store at −20 °C as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No T80643
Activity
  • Kinase Inhibitor
Cas No. 2050906-40-4
Molecular Weight 516.59
Product Type
  • Small Molecule Inhibitor
Signaling Pathway Tyrosine Kinase/Adaptors///Angiogenesis///JAK/STAT signaling
Target EGFR

Compound Overview

BEBT-109 (CAS 2050906-40-4) is a research-grade small molecule supplied by TargetMol.

Physical Properties

CAS Number 2050906-40-4
Molecular Formula C27H32N8O3
Molecular Weight 516.59 g/mol
Form Solid
Shipping Room Temperature (RT)

Biological Activity

BEBT-109 is a potent selective inhibitor of pan-mutant EGFR with enhanced pharmacokinetic properties, suitable for research on various mutant-EGFR-driven non-small cell lung cancer (NSCLC) (1).

Target(s): EGFR

Signaling pathway(s): Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling

Safety & Regulatory

For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.

Does prolonged sonication affect the compound structure?

It is recommended to sonicate at a lower frequency

How to store inhibitor products?

Solid-form products can be stored at -20°C for more than 3 years. Stock solutions are typically stored at -80°C and can be stored for more than 1 year. It is recommended to aliquot the product to avoid repeated freeze-thaw cycles. For short-term storage, samples can be kept at 4°C for more than one week.

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

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Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

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