BI 99179

SKU:BHB20407930
Overview
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BI 99179 (CAS 1291779-76-4) is a metabolic enzyme inhibitor supplied as a solid powder by TargetMol. For biochemical profiling and cell-based assay applications.
Activity Metabolic Enzyme Inhibitor
CAS No. 1291779-76-4
Molecular Weight 391.46 g/mol
Form Solid
Shipping Room Temperature
Options selector
Catalog no. Size
T14570-1MG 1 mg
T14570-5MG 5 mg
T14570-1MLX10MM 1 mL x 10 mM (in DMSO)
T14570-10MG 10 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 1 mg, 5 mg, 1 mL x 10 mM (in DMSO), 10 mg
  • Lead time: In Stock at Manufacturer — options listed in "Availability Content"; other statuses may take longer.
  • Storage: −20 °C
  • Shipping: Room temperature (RT) shipment.
  • Upon receipt: Store at −20 °C as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No T14570
Activity
  • Metabolic Enzyme Inhibitor
Alternative Names BI99179
Cas No. 1291779-76-4
Molecular Weight 391.46
Product Type
  • Small Molecule Inhibitor
Signaling Pathway Metabolism
SMILES N(C(=O)(CH)1C(CH)(NC(CC)=O)CC1)(C)C2=CC=C(C3=NC=4C(O3)=CC=CC4)C=C2
Target Fatty Acid Synthase

Compound Overview

BI 99179 (CAS 1291779-76-4) is a research-grade small molecule supplied by TargetMol.

Alternative names: BI99179

Physical Properties

CAS Number 1291779-76-4
Molecular Formula C23H25N3O3
Molecular Weight 391.46 g/mol
SMILES N(C(=O)(CH)1C(CH)(NC(CC)=O)CC1)(C)C2=CC=C(C3=NC=4C(O3)=CC=CC4)C=C2
Form Solid
Shipping Room Temperature (RT)

Biological Activity

BI99179 is a potent and selective type I fatty acid synthase (FAS) inhibitor with an IC50 of 79 nM and it exhibits significant exposure (both peripheral and central) upon oral administration in rats(1).

Target(s): Fatty Acid Synthase

Signaling pathway(s): Metabolism

Safety & Regulatory

For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.

Can inhibitors be used for cell experiments?

Yes — TargetMol inhibitors can be used in cell-based and in vitro experiments. Prepare a DMSO stock, then dilute into cell culture medium to the desired working concentration, keeping DMSO ≤ 0.1% (v/v) to avoid solvent toxicity. Note that not all compounds have published data for every cell line or assay system; in such cases, perform a dose-response experiment with appropriate positive and vehicle controls to validate efficacy in your specific model.

How do you ensure the quality and purity of compounds?

The structure of compounds is confirmed through HNMR and purity is verified through HPLC or LCMS, with most compounds having a purity of over 98%. Each batch comes with a Certificate of Analysis (COA), and testing reports are also displayed on our official website.

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

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Try Celltrypse Free – Request Your Sample Today

Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

Try Celltrypse Free – Request Your Sample Today