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Compound Overview
Biotin-PEG1-azide (CAS 1204085-48-2) is a research-grade small molecule supplied by TargetMol.
Physical Properties
| CAS Number | 1204085-48-2 |
|---|---|
| Molecular Formula | C14H24N6O3S |
| Molecular Weight | 356.45 g/mol |
| SMILES | (H)(C)12CS(CH)(CCCCC(=O)NCCOCCN=(N+)=(N-))(C)1((H))NC(=O)N2 |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
Biotin-PEG1-azide is a cleavable 1-unit polyethylene glycol (PEG) linker employed in the synthesis of antibody-drug conjugates (ADCs).
Target(s): Others, ADC Linker
Signaling pathway(s): Others, Antibody-drug Conjugate/ADC Related
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
It is recommended to sonicate at a lower frequency
When solubility is listed as < 1 mg/mL, the compound dissolves to less than 1 mg per milliliter in water at 25 °C, pH 7.4. Such compounds require an organic co-solvent such as DMSO to prepare a concentrated stock, which is then diluted into aqueous assay buffer. For cell-based assays, keep the final DMSO concentration below 0.1% (v/v) to avoid solvent-induced cytotoxicity.
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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