| Field | Specification |
|---|---|
| Mfr No | |
| Clonality | |
| Host | |
| Immunogen | H3396 cultured line established from a metastasis of a human breast adenocarcinoma was used as the immunogen for the Blood Group Lewis y antibody. |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage | |
| Target |
Overview
Blood Group Lewis y Antibody is an antibody targeting Blood. Host: Rabbit. Monoclonal. Clone: LWY/9243R. Format: Purified. Applications: IHC-P.
Key elements and design rationale
- Target: Blood.
- Immunogen: H3396 cultured line established from a metastasis of a human breast adenocarcinoma was used as the immunogen for the Bl….
- Species reactivity: Human.
- Localization: Cell membrane, Cytoplasm, Extracellular.
- Conjugate: Unconjugated (no label listed).
Biological background (from provided description)
This antibody recognizes a carbohydrate epitope present on tumor-associated Lewis Y antigen (Fucalpha1-2Galbeta1-4/3[Fucalpha1-3/4]GlcNAcbeta-). Lewis Y is expressed in large bowel tumors and colorectal carcinomas. It may be useful in the classification of human renal and bladder tumors.
Common research applications
- IHC: tissue distribution assessment; interpret with matched controls.
Notes for experimental interpretation
- Account for isoforms, paralogs, and post-translational modifications when interpreting signal.
- Support specificity with biological controls (e.g., KO/KD where available) and technical controls (e.g., secondary-only/isotype).
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
