| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | N1-(2-aminophenyl)-N8-phenyloctanediamide |
| Cas No. | |
| Form | Tan Solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble in 25 mg/ml DMSO or 10 mg/ml Ethanol |
| Source | Synthetic |
| Storage |
Bml-210 is a novel non-hydroxamic acid histone deacetylase (HDAC) inhibitor that has shown promising activity in epigenetic modulation. Although its primary research applications have been in oncology, particularly in inducing growth inhibition, apoptosis, and differentiation in leukemia cell lines, its mechanism of action is increasingly relevant to neuroscience. HDAC inhibitors are being explored for their neuroprotective effects, especially in the context of neurodegenerative diseases such as Alzheimer's and Huntington's disease. By modulating chromatin structure and gene expression, Bml-210 may influence neuronal plasticity, memory formation, and neuroinflammation. Its non-hydroxamic acid structure offers a unique pharmacological profile, potentially reducing off-target effects and improving therapeutic specificity. As interest in epigenetic therapies for neurological disorders grows, Bml-210 represents a valuable tool for probing the role of HDACs in the central nervous system.
Classification: Caution- Substance not yet fully tested.
Safety Phrases:
- S22 - Do not breathe dust
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
- S24/25- Avoid contact with skin and eyes
Hazard Statements:
H413 – May cause long lasting harmful effects to aquatic life.
Bml-210 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-348)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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2. Herman D., et al. (2006) Nature Chem. Biol. 10: 551.
