| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | 4-[[4-[(Aminoiminomethyl)amino]benzoyl]oxy]benzeneacetic acid 2-(dimethylamino)-2-oxoethyl ester methanesulfonate; FOY 305; FOY-S 980; Foipan mesylate |
| Cas No. | |
| Form | Off-white powder |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | May be dissolved in DMSO (50 mg/mL) or Water (50mg/mL) |
| Source | Synthetic |
| Storage |
Camostat mesylate is an orally bioavailable serine protease inhibitor best known for its inhibition of TMPRSS2, a key enzyme facilitating viral entry in respiratory infections such as COVID-19. While its primary research focus lies in infectious disease and fibrosis, Camostat’s modulation of protease activity has implications for neuroinflammation and blood-brain barrier integrity.
Emerging studies suggest potential roles in neurodegenerative disease models where protease dysregulation contributes to pathology. Its anti-fibrotic and anti-inflammatory properties also make it a candidate for repurposing in neurological contexts involving chronic inflammation or glial activation.
General Classification:
Warning Hazard statements: H315-H319-H335-H400 Precautionary statements: P261-P273-P305 + P351 + P338
Camostat mesylate (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-585)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
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- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
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2. Hsieh H. P., Hsu, J. T. (2007). Current Pharmaceutical Design. 13 (34): 3531–3542.
3. Kitamura K., Tomita K. (2012). Clinical and Experimental Nephrology. 16 (1): 44–48. 4. Kawase M., Shirato K., van der Hoek L., Taguchi F., Matsuyama S. (2012) J Virol. 86(12): 6537-6545. 5.. Hoffman M., et al. (2020) Cell: https://doi.org/10.1016/j.cell.2020.02.052