CCT128930

SKU:BHB20433157
Overview
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CCT128930 (CAS 885499-61-6) is a kinase inhibitor supplied as a solid powder by TargetMol. For biochemical profiling and cell-based assay applications.
Activity Kinase Inhibitor
CAS No. 885499-61-6
Molecular Weight 341.84 g/mol
Form Solid
Shipping Room Temperature
Options selector
Catalog no. Size
T6303-2MG 2 mg
T6303-5MG 5 mg
T6303-1MLX10MM 1 mL x 10 mM (in DMSO)
T6303-10MG 10 mg
T6303-25MG 25 mg
T6303-50MG 50 mg
T6303-100MG 100 mg
T6303-200MG 200 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 2 mg, 5 mg, 1 mL x 10 mM (in DMSO), 10 mg, 25 mg, 50 mg, 100 mg, 200 mg
  • Lead time: In Stock at Manufacturer — options listed in "Availability Content"; other statuses may take longer.
  • Storage: −20 °C
  • Shipping: Room temperature (RT) shipment.
  • Upon receipt: Store at −20 °C as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No T6303
Activity
  • Kinase Inhibitor
Cas No. 885499-61-6
Molecular Weight 341.84
Product Type
  • Small Molecule Inhibitor
Signaling Pathway Cytoskeletal Signaling///MAPK///Tyrosine Kinase/Adaptors///Autophagy///PI3K/Akt/mTOR signaling
SMILES C(C1(N)CCN(C2=C3C(=NC=N2)NC=C3)CC1)C4=CC=C(Cl)C=C4
Target S6 Kinase///Autophagy///PKA///Akt

Compound Overview

CCT128930 (CAS 885499-61-6) is a research-grade small molecule supplied by TargetMol.

Physical Properties

CAS Number 885499-61-6
Molecular Formula C18H20ClN5
Molecular Weight 341.84 g/mol
SMILES C(C1(N)CCN(C2=C3C(=NC=N2)NC=C3)CC1)C4=CC=C(Cl)C=C4
Form Solid
Shipping Room Temperature (RT)

Biological Activity

CCT128930 is a potent, ATP-competitive and selective inhibitor of Akt2 with IC50 of 6 nM, 28-fold greater selectivity for Akt2 than the closely related PKA kinase.

Target(s): S6 Kinase, Autophagy, PKA, Akt

Signaling pathway(s): Cytoskeletal Signaling, MAPK, Tyrosine Kinase/Adaptors, Autophagy, PI3K/Akt/mTOR signaling

Safety & Regulatory

For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.

Does prolonged sonication affect the compound structure?

It is recommended to sonicate at a lower frequency

what frequency should sonication be used?

Use a bath-type ultrasonic cleaner at standard cleaning frequency (37–40 kHz). Bath sonication is gentler than a probe sonicator and avoids sample overheating. Sonicate in 5–10 second intervals, checking solubility between pulses, for no more than 2–3 minutes total. Warm the bath to 37 °C if solubility remains poor.

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

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