| Field | Specification |
|---|---|
| Mfr No | |
| Clonality | |
| Host | |
| Immunogen | PBLs from a NK-leukemia patient were used as the immunogen for the was used as the immunogen for the CD16 antibody. |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage | |
| Target | |
| UniProt # |
Overview
CD16 Antibody is an antibody targeting CD16. Host: Mouse. Monoclonal. Clone: CB16. Format: Purified. Applications: FACS.
Key elements and design rationale
- Target: CD16.
- Immunogen: PBLs from a NK-leukemia patient were used as the immunogen for the was used as the immunogen for the CD16 antibody..
- Species reactivity: Human.
- Localization: Cell membrane, Secreted.
- Conjugate: Unconjugated (no label listed).
Biological background (from provided description)
It recognizes CD16 (FcgammaRIII), the low-affinity receptor for IgG with an apparent molecular weight of 50-80kDa. CD16 is represented by two similar genes, CD16A (FcgammaRIIIA), which exists as a hetero-oligomeric polypeptide-anchored form in macrophages and NK cells and CD16B (FcgammaRIIIB), which exist as a monomeric GPI-anchored form in neutrophils.
Common research applications
- Suitable for antibody-based detection workflows where target signal comparison and localization are required.
Notes for experimental interpretation
- Account for isoforms, paralogs, and post-translational modifications when interpreting signal.
- Support specificity with biological controls (e.g., KO/KD where available) and technical controls (e.g., secondary-only/isotype).
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.