| Field | Specification |
|---|---|
| Mfr No | |
| Clonality | |
| Host | |
| Immunogen | A synthesized peptide derived from human Ceruloplasmin was used as the immunogen for the Ceruloplasmin antibody. |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage | |
| Target | |
| UniProt # |
Overview
Ceruloplasmin Antibody / CP is a anti-CP Rabbit antibody Recombinant Rabbit Monoclonal clone 31C62 supplied in Liquid format. Recommended for workflows such as Western blot (WB) with listed reactivity in Human, Rat.
Key elements and design rationale
- Target: CP
- Antibody details: Rabbit, Recombinant Rabbit Monoclonal, clone 31C62, isotype Rabbit IgG
- Format: Liquid
- Applications (as listed): WB
Biological background
Ceruloplasmin antibody is widely applied in studies of metabolism, neurodegeneration, and inflammatory disease. Abnormal ceruloplasmin levels are associated with Wilson disease, aceruloplasminemia, and other disorders of copper metabolism. In addition, altered expression occurs in Parkinson disease and Alzheimer disease, where oxidative stress contributes to pathogenesis. By detecting ceruloplasmin, researchers can evaluate copper homeostasis and its links to neurological disorders.
In western blot assays, ceruloplasmin antibody detects protein bands of the expected size in serum and liver extracts. Immunohistochemistry highlights hepatocyte production and distribution in tissues, while ELISA applications support quantification of ceruloplasmin levels in plasma. These methods make ceruloplasmin antibody useful for both clinical and experimental research.
Ceruloplasmin also acts as an acute phase reactant, with levels rising during inflammation and infection. Elevated ceruloplasmin is observed in autoimmune disease, cardiovascular disease, and cancer. By applying ceruloplasmin antibody, scientists can study how changes in CP expression reflect inflammation and metabolic stress.
Ceruloplasmin antibody from
Research relevance and current trends
- Connecting protein-level changes to phenotype using orthogonal readouts (genetic perturbation, transcriptomics, imaging).
- Considering isoforms and post-translational regulation when interpreting protein-level changes.
- Comparing results across species and model systems with matched controls.
Common research applications
- Western blotting: compare relative abundance and activation-state changes across conditions.
Interpret changes in signal alongside appropriate controls and, when relevant, in parallel with total-protein or pathway readouts.
Notes for experimental interpretation
- Signal can reflect expression level, isoform composition, and post-translational state; interpret results in the context of your model system and stimuli.
- Species differences and sample matrices can influence epitope recognition; prioritize matched controls and orthogonal confirmation when feasible.
Antibody notes: Monoclonal antibodies provide a defined epitope recognition profile that can support consistent comparisons across experiments.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
