| Field | Specification |
|---|---|
| Mfr No | |
| Clonality | |
| Host | |
| Immunogen | A peptide sequence specific to Charged multivesicular body protein 2b protein was used as the immunogen for the CHMP2B antibody. |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage | |
| Target | |
| UniProt # |
Overview
CHMP2B Antibody / Charged multivesicular body protein 2b is a anti-CHMP2B Rabbit antibody Recombinant Rabbit Monoclonal clone 25C36 supplied in Purified format. Recommended for workflows such as Western blot (WB), IHC-P, Immunoprecipitation (IP) with listed reactivity in Human. Reported localization: Cytoplasm.
Key elements and design rationale
- Target: CHMP2B
- Antibody details: Rabbit, Recombinant Rabbit Monoclonal, clone 25C36, isotype Rabbit IgG
- Format: Purified
- Applications (as listed): WB, IHC-P, IP
Biological background
Mutations in CHMP2B have been linked to neurodegenerative disorders, including frontotemporal dementia and amyotrophic lateral sclerosis. Research on CHMP2B helps elucidate mechanisms of vesicular transport, neuronal maintenance, and protein quality control, making it relevant in both basic and disease-focused studies.
Using a high-quality CHMP2B antibody enables accurate detection in applications such as western blot, immunohistochemistry, and immunofluorescence. A CHMP2B antibody from
Research relevance and current trends
- Connecting protein-level changes to phenotype using orthogonal readouts (genetic perturbation, transcriptomics, imaging).
- Considering isoforms and post-translational regulation when interpreting protein-level changes.
- Comparing results across species and model systems with matched controls.
Common research applications
- Western blotting: compare relative abundance and activation-state changes across conditions.
- Immunohistochemistry: map target signal in tissue context and compare regions/phenotypes.
Interpret changes in signal alongside appropriate controls and, when relevant, in parallel with total-protein or pathway readouts.
Notes for experimental interpretation
- Signal can reflect expression level, isoform composition, and post-translational state; interpret results in the context of your model system and stimuli.
- Species differences and sample matrices can influence epitope recognition; prioritize matched controls and orthogonal confirmation when feasible.
Antibody notes: Monoclonal antibodies provide a defined epitope recognition profile that can support consistent comparisons across experiments.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
