CIRBP Antibody / Cold-inducible RNA-binding protein

SKU:BHA17136327
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NSJ Bioreagents
NSJ Bioreagents
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Overview
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Anti-CIRBP antibody from Rabbit, recombinant rabbit monoclonal, clone 26C38, Rabbit IgG. Recommended for workflows such as Western blot (WB), IHC-P. Reactivity: Human. Supplied as purified format.
Target CIRBP
Clone Number 26C38
Host Rabbit
Reactivity Human
Application WB, IHC-P
Options selector
Catalog no. Formulation Size
RQ8908 Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Formulation: Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA; Size: 100 ul
  • Lead time: typically ships in ~2-3 business days; timing may vary by selected option.
  • Storage: After reconstitution, the CIRBP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • Shipping: cold-chain shipment (typically with ice packs).
  • Upon receipt: store at the recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No RQ8908
Clonality
  • Recombinant Rabbit Monoclonal
Host Rabbit
Immunogen A peptide sequence specific to Cold-inducible RNA-binding protein was used as the immunogen for the CIRBP antibody.
Isotype
  • Rabbit IgG
Product Type
  • Antibodies
  • Primary Antibodies
Purity Affinity chromatography
Reactivity
  • Human
Storage After reconstitution, the CIRBP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Target CIRBP
UniProt # Q14011

Overview

CIRBP Antibody / Cold-inducible RNA-binding protein is a anti-CIRBP Rabbit antibody Recombinant Rabbit Monoclonal clone 26C38 supplied in Purified format. Recommended for workflows such as Western blot (WB), IHC-P with listed reactivity in Human. Reported localization: Nuclear, cytoplasmic.

Key elements and design rationale

  • Target: CIRBP
  • Antibody details: Rabbit, Recombinant Rabbit Monoclonal, clone 26C38, isotype Rabbit IgG
  • Format: Purified
  • Applications (as listed): WB, IHC-P

Biological background

Cold-inducible RNA-binding protein (CIRBP) is a stress-response protein that binds to RNA and modulates mRNA stability and translation. It is upregulated in response to mild hypothermia, ultraviolet radiation, and other cellular stressors, helping to regulate gene expression under challenging environmental conditions.

CIRBP plays roles in cell proliferation, circadian rhythm regulation, and protection against apoptosis. It has been implicated in processes such as spermatogenesis, inflammation, and tumor progression. Altered CIRBP expression or function can influence cellular stress adaptation and disease development, making it a valuable target for molecular and biomedical research.

Using a high-quality CIRBP antibody allows precise detection in applications such as western blot, immunohistochemistry, and immunofluorescence. A CIRBP antibody from

Research relevance and current trends

  • Connecting protein-level changes to phenotype using orthogonal readouts (genetic perturbation, transcriptomics, imaging).
  • Considering isoforms and post-translational regulation when interpreting protein-level changes.
  • Comparing results across species and model systems with matched controls.

Common research applications

  • Western blotting: compare relative abundance and activation-state changes across conditions.
  • Immunohistochemistry: map target signal in tissue context and compare regions/phenotypes.

Interpret changes in signal alongside appropriate controls and, when relevant, in parallel with total-protein or pathway readouts.

Notes for experimental interpretation

  • Signal can reflect expression level, isoform composition, and post-translational state; interpret results in the context of your model system and stimuli.
  • Species differences and sample matrices can influence epitope recognition; prioritize matched controls and orthogonal confirmation when feasible.

Antibody notes: Monoclonal antibodies provide a defined epitope recognition profile that can support consistent comparisons across experiments.

Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.

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Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

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